Gene Symbol | ACLY |
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Entrez Gene | 47 |
Alt Symbol | ACL, ATPCL, CLATP |
Species | Human |
Gene Type | protein-coding |
Description | ATP citrate lyase |
Other Description | ATP citrate synthase|ATP-citrate (pro-S-)-lyase|ATP-citrate synthase|citrate cleavage enzyme |
Swissprots | Q9BRL0 B4DIM0 B4E3P0 P53396 Q13037 |
Accessions | EAW60777 EAW60778 EAW60779 EAW60780 EAW60781 P53396 AB210035 BAE06117 AK095084 BAC04484 AK295675 BAG58532 AK304802 BAG65552 AK312315 BC006195 AAH06195 BG037168 DB072009 DQ575356 JF432308 ADZ15525 U18197 AAB60340 X64330 CAA45614 XM_005257395 XP_005257452 NM_001096 NP_001087 NM_001303274 NP_001290203 NM_001303275 NP_001290204 NM_198830 NP_942127 |
Function | ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine. {ECO:0000269|PubMed:23932781}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Citrate cycle (TCA cycle) |
ACLY - MBS1268164 from MyBioSource
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Human ACLY cDNA clone(NM_198830.1) - CDFG012932 from Creative Biomart
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Human ACLY cDNA clone(NM_001096.2) - CDFH000185 from Creative Biomart
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Human ACLY ORF Clone(NM_001096.2) - CDCL152920 from Creative Biomart
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Human ACLY ORF Clone(NM_198830.1) - CDCR326236 from Creative Biomart
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Human ACLY ORF Clone(NM_198830.1) - CDCR326237 from Creative Biomart
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Human ACLY ORF Clone(NM_001096.2) - CDCR346384 from Creative Biomart
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Human ACLY ORF Clone(NM_001096.2) - CDCR346385 from Creative Biomart
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Human ACLY ORF clone (NM_001096.2) - CDCR023772 from Creative biogene
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Human ACLY ORF clone (NM_198830.1) - CDCR023774 from Creative biogene
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Human ACLY ORF Clone (BC006195) - CDCS407392 from Creative biogene
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Human ACLY cDNA Clone(NM_198830.1) - CDFG012932 from Creative biogene
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Human ACLY cDNA Clone(NM_001096.2) - CDFH000185 from Creative biogene
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