Gene Symbol | ACLY |
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Entrez Gene | 47 |
Alt Symbol | ACL, ATPCL, CLATP |
Species | Human |
Gene Type | protein-coding |
Description | ATP citrate lyase |
Other Description | ATP citrate synthase|ATP-citrate (pro-S-)-lyase|ATP-citrate synthase|citrate cleavage enzyme |
Swissprots | Q9BRL0 B4DIM0 B4E3P0 P53396 Q13037 |
Accessions | EAW60777 EAW60778 EAW60779 EAW60780 EAW60781 P53396 AB210035 BAE06117 AK095084 BAC04484 AK295675 BAG58532 AK304802 BAG65552 AK312315 BC006195 AAH06195 BG037168 DB072009 DQ575356 JF432308 ADZ15525 U18197 AAB60340 X64330 CAA45614 XM_005257395 XP_005257452 NM_001096 NP_001087 NM_001303274 NP_001290203 NM_001303275 NP_001290204 NM_198830 NP_942127 |
Function | ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine. {ECO:0000269|PubMed:23932781}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Citrate cycle (TCA cycle) |
Active human ATP citrate lyase full length protein - ab196090 from Abcam
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ACLY / ATP Citrate Lyase Antibody Blocking Peptide - LS-E15737 from LifeSpan Bioscience
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ACLY / ATP Citrate Lyase Antibody Blocking Peptide - LS-E15736 from LifeSpan Bioscience
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Human ACLY protein (His Tag) - orb138118 from Biorbyt
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ACLY Blocking Peptide - 33R-5389 from Fitzgerald
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ACLY Blocking Peptide - 33R-8779 from Fitzgerald
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ACLY fusion protein - Ag7709 from Proteintech Group
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ACLY fusion protein - Ag7940 from Proteintech Group
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Recombinant Human ACLY, His tagged - ACLY-2488H from Creative Biomart
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Recombinant Human ACLY, GST-tagged - ACLY-9291H from Creative Biomart
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Recombinant Human ATP Citrate Lyase, GST-tagged - ACLY-420H from Creative Biomart
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Human ACLY / acly / ATP citrate lyase Protein (His Tag) - 11769-H07B-20 from Sino Biological
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ATP-Citrate synthase (P449) Peptide - BS1715P from Bioworld Technology
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Recombinant Human ATP-citrate synthase(ACLY) ,partial - CSB-YP001158HU CSB-EP001158HU CSB-BP001158HU CSB-MP001158HU from Cusabio
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Akt2, active - MBS637464 from MyBioSource
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Akt2, active - MBS635852 from MyBioSource
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ACLY Blocking Peptide - abx161763 from Abbexa
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ATP-citrate synthase (transcript variant 1) - TP300508 from Acris Antibodies
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ATP-citrate synthase(ACLY) ,partial, Recombinant Protein - MBS953878 from MyBioSource
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Recombinant Human ACLY / acly / ATP citrate lyase Protein (His tag) - PKSH031004 from Elabscience
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Recombinant Homo sapiens (Human) ATP-citrate synthase - CSB-EP001158HU from Cusabio
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ATP Citrate Lyase Protein - NBP1-90269PEP from Novus Biologicals
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ATP Citrate Lyase Protein - NBP1-90268PEP from Novus Biologicals
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ATP Citrate Lyase Recombinant Protein Antigen - NBP1-90267PEP from Novus Biologicals
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ATP Citrate Lyase Recombinant Protein Antigen - NBP1-90266PEP from Novus Biologicals
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