ACLY

Gene Symbol ACLY
Entrez Gene 47
Alt Symbol ACL, ATPCL, CLATP
Species Human
Gene Type protein-coding
Description ATP citrate lyase
Other Description ATP citrate synthase|ATP-citrate (pro-S-)-lyase|ATP-citrate synthase|citrate cleavage enzyme
Swissprots Q9BRL0 B4DIM0 B4E3P0 P53396 Q13037
Accessions EAW60777 EAW60778 EAW60779 EAW60780 EAW60781 P53396 AB210035 BAE06117 AK095084 BAC04484 AK295675 BAG58532 AK304802 BAG65552 AK312315 BC006195 AAH06195 BG037168 DB072009 DQ575356 JF432308 ADZ15525 U18197 AAB60340 X64330 CAA45614 XM_005257395 XP_005257452 NM_001096 NP_001087 NM_001303274 NP_001290203 NM_001303275 NP_001290204 NM_198830 NP_942127
Function ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine. {ECO:0000269|PubMed:23932781}.
Subcellular Location Cytoplasm.
Top Pathways Citrate cycle (TCA cycle)

ATP-citrate synthase CRISPR/Cas9 KO Plasmid (h) - sc-403146 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP-citrate synthase HDR Plasmid (h) - sc-403146-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP-citrate synthase Double Nickase Plasmid (h) - sc-403146-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP-citrate synthase Double Nickase Plasmid (h2) - sc-403146-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP-citrate synthase CRISPR Activation Plasmid (h) - sc-403146-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP-citrate synthase CRISPR Activation Plasmid (h2) - sc-403146-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP-citrate synthase Lentiviral Activation Particles (h) - sc-403146-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP-citrate synthase Lentiviral Activation Particles (h2) - sc-403146-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP-citrate synthase siRNA (h) - sc-45206 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATP-citrate synthase shRNA Plasmid (h) - sc-45206-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATP-citrate synthase shRNA (h) Lentiviral Particles - sc-45206-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATP Citrate Lyase RNAi - H00000047-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ATP Citrate Lyase RNAi - H00000047-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU081921 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2719 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2719 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ACLY siRNA (Human) - CRH0035 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACLY - MBS827995 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ACLY (NM_001096.2) - SHH230290 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ACLY(NM_001096.2) - SHG029647 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ACLY(NM_198830.1) - SHG029665 from Creative biogene

Category siRNA
Species Reactivities Human

ACLY shRNA Plasmid (Human) - CHH0035 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ACLY miRNA 3'UTR clone - MiUTR1H-00102 from Creative biogene

Species Reactivities Human

ACLY miRNA 3'UTR clone - MiUTR1H-00103 from Creative biogene

Species Reactivities Human
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