DGAT1

Gene Symbol	DGAT1
Entrez Gene	8694
Alt Symbol	ARAT, ARGP1, DGAT, DIAR7
Species	Human
Gene Type	protein-coding
Description	diacylglycerol O-acyltransferase 1
Other Description	ACAT related gene product 1|acyl coenzyme A:cholesterol acyltransferase related gene 1|acyl-CoA retinol O-fatty-acyltransferase|acyl-CoA:diacylglycerol acyltransferase|diglyceride acyltransferase
Swissprots	B2RWQ2 Q96BB8 O75907 D3DWL6
Accessions	EAW82127 EAW82128 EAW82129 EAW82130 O75907 AB057815 BAC66170 AF059202 AAC63997 BC006263 AAH06263 BC015762 AAH15762 BC023565 AAH23565 BC106084 AAI06085 BC150649 AAI50650 BI907285 CK300256 DQ892286 ABM83212 DQ895486 ABM86412 HY016503 XM_011517356 XP_011515658 NM_012079 NP_036211
Function	Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. {ECO:0000269|PubMed:16214399, ECO:0000269|PubMed:9756920}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways	Fat digestion and absorption, Glycerolipid metabolism, Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DGAT1 peptide - ab118966 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

DGAT1 Antibody Blocking Peptide - LS-E27720 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DGAT1 Antibody Blocking Peptide - LS-E26238 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DGAT1 Antibody Blocking Peptide - LS-E23125 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DGAT1 (Internal) blocking peptide - GTX89165-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

DGAT1 blocking peptide - GTX89164-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

DGAT1 Blocking Peptide - 33R-10954 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Human DGAT1 Protein - abx066320 from Abbexa Category Protein Source E.coli Species Human

DGAT1 Peptide - AC21-1070-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DGAT1 Peptide - AC21-2855-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1), Human - 20-9356 from ARP American Research Products Category Protein Prices $449.00 Sizes 50 µg Source E.coli Species Human

DGAT1 Peptide - 45-475P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human, Rat

DGAT1 fusion protein - ag0437 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DGAT1 fusion protein - Ag2123 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human DGAT1, GST-tagged - DGAT1-23H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human DGAT1 - DGAT1-727H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1) - RPJ273Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1) - RPJ273Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1) - RPJ273Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1) - RPJ273Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1) - RPJ273Hu01 from Cloud-clone Category Protein Source E.coli Species Human

DGAT1 Blocking Peptide - 3845BP-50 from Biovision Category Peptide Prices $95.00 Sizes 50 µg

DGAT1, Peptide - MBS843531 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

DGAT1, Peptide - MBS428091 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

DGAT1, Peptide - MBS425795 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

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