Gene Symbol | EVC |
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Entrez Gene | 2121 |
Alt Symbol | DWF-1, EVC1, EVCL |
Species | Human |
Gene Type | protein-coding |
Description | Ellis van Creveld protein |
Other Description | Ellis van Creveld syndrome|ellis-van Creveld syndrome protein |
Swissprots | P57679 |
Accessions | AAY40958 AAY41049 P57679 AF216184 AAF37216 AF216185 AAF37217 AF239742 AAF44682 AK025394 BC085608 AAH85608 BM670090 XM_005247952 XP_005248009 XM_006713865 XP_006713928 XM_006713866 XP_006713929 XM_011513419 XP_011511721 XR_427473 XR_427475 XR_427476 XR_924920 XR_924921 XR_924922 XR_924923 XR_924924 XR_924925 XR_924926 XR_924927 XR_924928 NM_001306090 NP_001293019 NM_001306092 NP_001293021 NM_153717 NP_714928 NM_014556 |
Function | Acts as a positive mediator of Hedgehog signaling indispensable for normal endochondral growth and skeletal development. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Cell projection, cilium membrane {ECO:0000250}. Note=EVC2 is required for the localization of EVC at the base of primary cilia. {ECO:0000250}. |
Tissue Specificity | Found in the developing vertebral bodies, ribs, upper and lower limbs, heart, kidney, lung. |
EVC (H-300) - sc-134873 from Santa Cruz Biotechnology
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EVC (H-1) - sc-271955 from Santa Cruz Biotechnology
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EVC (M-300) - sc-134874 from Santa Cruz Biotechnology
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EVC (N-20) - sc-51287 from Santa Cruz Biotechnology
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EVC (L-19) - sc-51286 from Santa Cruz Biotechnology
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Anti-Ellis van Creveld syndrome antibody - ab72808 from Abcam
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Anti-Ellis van Creveld syndrome antibody [EPR10408] - ab171952 from Abcam
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Anti-EVC / DWF-1 Antibody - LS-C307441 from LifeSpan Bioscience
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Anti-EVC / DWF-1 Antibody (clone 3C4) - LS-C197167 from LifeSpan Bioscience
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Ellis van Creveld syndrome Antibody - NBP1-84039 from Novus Biologicals
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Ellis van Creveld syndrome Antibody - NBP1-84038 from Novus Biologicals
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Ellis van Creveld syndrome Antibody - H00002121-B01P from Novus Biologicals
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Ellis van Creveld syndrome Antibody (3C4) - H00002121-M06 from Novus Biologicals
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EVC1 Polyclonal Antibody - bs-11282R from Bioss
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EVC1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11282R-A350 from Bioss
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EVC1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11282R-A488 from Bioss
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EVC1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11282R-A555 from Bioss
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EVC1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11282R-A647 from Bioss
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EVC1 Polyclonal Antibody, Cy3 Conjugated - bs-11282R-Cy3 from Bioss
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EVC1 Polyclonal Antibody, Cy5 Conjugated - bs-11282R-Cy5 from Bioss
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EVC1 Polyclonal Antibody, Cy5.5 Conjugated - bs-11282R-Cy5.5 from Bioss
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EVC1 Polyclonal Antibody, Cy7 Conjugated - bs-11282R-Cy7 from Bioss
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EVC1 Polyclonal Antibody, FITC Conjugated - bs-11282R-FITC from Bioss
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EVC1 Polyclonal Antibody, Biotin Conjugated - bs-11282R-Biotin from Bioss
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EVC1 Polyclonal Antibody, HRP Conjugated - bs-11282R-HRP from Bioss
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