Gene Symbol | EVC |
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Entrez Gene | 2121 |
Alt Symbol | DWF-1, EVC1, EVCL |
Species | Human |
Gene Type | protein-coding |
Description | Ellis van Creveld protein |
Other Description | Ellis van Creveld syndrome|ellis-van Creveld syndrome protein |
Swissprots | P57679 |
Accessions | AAY40958 AAY41049 P57679 AF216184 AAF37216 AF216185 AAF37217 AF239742 AAF44682 AK025394 BC085608 AAH85608 BM670090 XM_005247952 XP_005248009 XM_006713865 XP_006713928 XM_006713866 XP_006713929 XM_011513419 XP_011511721 XR_427473 XR_427475 XR_427476 XR_924920 XR_924921 XR_924922 XR_924923 XR_924924 XR_924925 XR_924926 XR_924927 XR_924928 NM_001306090 NP_001293019 NM_001306092 NP_001293021 NM_153717 NP_714928 NM_014556 |
Function | Acts as a positive mediator of Hedgehog signaling indispensable for normal endochondral growth and skeletal development. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Cell projection, cilium membrane {ECO:0000250}. Note=EVC2 is required for the localization of EVC at the base of primary cilia. {ECO:0000250}. |
Tissue Specificity | Found in the developing vertebral bodies, ribs, upper and lower limbs, heart, kidney, lung. |
Human Ellis van Creveld syndrome full length protein - ab158391 from Abcam
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Human Ellis van Creveld syndrome protein fragment - ab158392 from Abcam
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Recombinant Human Ellis van Creveld syndrome Protein - H00002121-Q01 from Novus Biologicals
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Recombinant Human Ellis van Creveld syndrome Protein - H00002121-P01 from Novus Biologicals
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EVC - H00002121-P01-10 from Acris Antibodies
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EVC - H00002121-P01-25 from Acris Antibodies
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EVC - H00002121-Q01-10 from Acris Antibodies
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EVC - H00002121-Q01-25 from Acris Antibodies
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Recombinant Human Ellis-van Creveld syndrome protein(EVC) - CSB-YP007862HU CSB-EP007862HU CSB-BP007862HU CSB-MP007862HU from Cusabio
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EVC - TP324382 from Acris Antibodies
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Ellis van Creveld syndrome Recombinant Protein Antigen - NBP1-84039PEP from Novus Biologicals
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Ellis van Creveld syndrome Recombinant Protein Antigen - NBP1-84038PEP from Novus Biologicals
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EVC-Antibody-N-term-Blocking-Peptide - BP9590a from Abgent, a WuXi AppTec company
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EVC Peptide, Human - M34GP05111H from Creative Peptides
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Ellis-van Creveld syndrome protein (EVC), Recombinant Protein - MBS960555 from MyBioSource
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