EVC

Gene Symbol EVC
Entrez Gene 2121
Alt Symbol DWF-1, EVC1, EVCL
Species Human
Gene Type protein-coding
Description Ellis van Creveld protein
Other Description Ellis van Creveld syndrome|ellis-van Creveld syndrome protein
Swissprots P57679
Accessions AAY40958 AAY41049 P57679 AF216184 AAF37216 AF216185 AAF37217 AF239742 AAF44682 AK025394 BC085608 AAH85608 BM670090 XM_005247952 XP_005248009 XM_006713865 XP_006713928 XM_006713866 XP_006713929 XM_011513419 XP_011511721 XR_427473 XR_427475 XR_427476 XR_924920 XR_924921 XR_924922 XR_924923 XR_924924 XR_924925 XR_924926 XR_924927 XR_924928 NM_001306090 NP_001293019 NM_001306092 NP_001293021 NM_153717 NP_714928 NM_014556
Function Acts as a positive mediator of Hedgehog signaling indispensable for normal endochondral growth and skeletal development. {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Cell projection, cilium membrane {ECO:0000250}. Note=EVC2 is required for the localization of EVC at the base of primary cilia. {ECO:0000250}.
Tissue Specificity Found in the developing vertebral bodies, ribs, upper and lower limbs, heart, kidney, lung.

EVC CRISPR/Cas9 KO Plasmid (h) - sc-409610 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EVC HDR Plasmid (h) - sc-409610-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EVC Double Nickase Plasmid (h) - sc-409610-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EVC Double Nickase Plasmid (h2) - sc-409610-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EVC CRISPR Activation Plasmid (h) - sc-409610-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EVC CRISPR Activation Plasmid (h2) - sc-409610-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EVC Lentiviral Activation Particles (h) - sc-409610-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EVC Lentiviral Activation Particles (h2) - sc-409610-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EVC siRNA (h) - sc-72235 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EVC shRNA Plasmid (h) - sc-72235-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EVC shRNA (h) Lentiviral Particles - sc-72235-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ellis van Creveld syndrome RNAi - H00002121-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN8017 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8017 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

EVC siRNA (Human) - CRH1474 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EVC - MBS828633 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EVC (NM_153717.2) - SHH287757 from Creative biogene

Category siRNA
Species Reactivities Human

Human EVC siRNA - orb261976 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EVC shRNA Plasmid (Human) - CHH1474 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EVC miRNA 3'UTR clone - MiUTR1H-03328 from Creative biogene

Species Reactivities Human
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