Gene Symbol | FBXO45 |
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Entrez Gene | 200933 |
Alt Symbol | Fbx45 |
Species | Human |
Gene Type | protein-coding |
Description | F-box protein 45 |
Other Description | F-box only protein 45|F-box/SPRY domain-containing protein 1|hFbxo45 |
Swissprots | A6NF90 P0C2W1 D3DXB5 |
Accessions | EAW53643 EAW53644 P0C2W1 AK025697 BC172382 AAI72382 BE047625 BE778263 CA445163 DB636510 NM_001105573 NP_001099043 |
Function | Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation. {ECO:0000250, ECO:0000269|PubMed:19581926}. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}. |
FBXO45 (W-16) - sc-99418 from Santa Cruz Biotechnology
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Anti-FBXO45 antibody - ab126521 from Abcam
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Anti-FBXO45 antibody - ab201219 from Abcam
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Anti-FBXO45 antibody - ab136614 from Abcam
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Anti-FBXO45 Antibody (aa107-156) - LS-C169575 from LifeSpan Bioscience
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FBXO45 Antibody - NBP1-91891 from Novus Biologicals
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FBXO45 Polyclonal Antibody - bs-13150R from Bioss
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FBXO45 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13150R-A350 from Bioss
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FBXO45 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13150R-A488 from Bioss
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FBXO45 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13150R-A555 from Bioss
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FBXO45 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13150R-A647 from Bioss
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FBXO45 Polyclonal Antibody, Cy3 Conjugated - bs-13150R-Cy3 from Bioss
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FBXO45 Polyclonal Antibody, Cy5 Conjugated - bs-13150R-Cy5 from Bioss
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FBXO45 Polyclonal Antibody, Cy5.5 Conjugated - bs-13150R-Cy5.5 from Bioss
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FBXO45 Polyclonal Antibody, Cy7 Conjugated - bs-13150R-Cy7 from Bioss
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FBXO45 Polyclonal Antibody, FITC Conjugated - bs-13150R-FITC from Bioss
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FBXO45 Polyclonal Antibody, Biotin Conjugated - bs-13150R-Biotin from Bioss
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FBXO45 Polyclonal Antibody, HRP Conjugated - bs-13150R-HRP from Bioss
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Anti-FBXO45 antibody produced in rabbit - HPA040730 from Sigma-Aldrich
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FBXO45 Antibody - middle region (ARP66799_P050) - ARP66799_P050 from Aviva Systems Biology
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Rabbit Anti-Human FBXO45 Polyclonal Antibody - DPABH-22873 from Creative Diagnostics
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Anti-FBXO45 (aa 107-156) polyclonal antibody - DPABH-26853 from Creative Diagnostics
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Anti-FBXO45 Antibody (aa83-115) - LS-C356739 from LifeSpan Bioscience
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FBXO45 Antibody - N-terminal region (OAAB19416) - OAAB19416 from Aviva Systems Biology
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FBXO45-Antibody-N-Term - AP21457a from Abgent, a WuXi AppTec company
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