CFH

Gene Symbol CFH
Entrez Gene 3075
Alt Symbol AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS
Species Human
Gene Type protein-coding
Description complement factor H
Other Description H factor 1 (complement)|H factor 2 (complement)|adrenomedullin binding protein|age-related maculopathy susceptibility 1|beta-1-H-globulin|beta-1H|factor H|factor H-like 1
Swissprots A5PL14 Q5TFM3 P78435 Q2TAZ5 Q14570 Q38G77 Q8N708 Q9NU86 P08603
Accessions AAB01987 ABB02180 AGZ15310 AHH32464 CAA82763 EAW91260 EAW91261 P08603 AI568119 AK225649 AK226113 AK291395 BAF84084 BC012610 BC037285 AAH37285 BC073982 BC110643 AAI10644 BC142699 AAI42700 BM842566 BP324193 JF432152 ADZ15369 M12383 AAA52013 M17517 AAA52016 M65294 AAA35948 X04697 CAB41739 X07523 CAA30403 Y00716 CAA68704 NM_000186 NP_000177 NM_001014975 NP_001014975
Function Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.
Subcellular Location Secreted.
Tissue Specificity Expressed by the liver and secreted in plasma.
Top Pathways Complement and coagulation cascades, Staphylococcus aureus infection

Factor H (C18/3) - sc-47685 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor H (C18/3): sc-47685. Immunoperoxidase staining of formalin fixed, paraffin-embedded human ovary tissue showing cytoplasmic staining of ovarian stroma cells and staining of plasma in blood vessels.

Factor H (D-8) - sc-398245 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor H (D-8): sc-398245. Western blot analysis of Factor H expression in K-562 whole cell lysate.

Factor H (H-5) - sc-166608 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor H (H-5): sc-166608. Western blot analysis of Factor H expression in human PBL whole cell lysate.

Factor H (H-300) - sc-33156 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Factor H (H-300): sc-33156. Western blot analysis of human recombinant Factor H fusion protein.

Factor H (H-7) - sc-166613 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor H (H-7): sc-166613. Western blot analysis of human Factor H protein purified from serum.

Factor H (M-300) - sc-33157 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Factor H (M-300): sc-33157. Western blot analysis of Factor H expression in mouse liver tissue extract.

Factor H (OX23) - sc-53066 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor H (OX23): sc-53066. Western blot analysis of human recombinant Factor H.

Factor H (Y-20) - sc-17949 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Factor H (Y-20): sc-17949. Western blot analysis of Factor H in human plasma.

Factor H (OX24) - sc-53067 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor H (OX24): sc-53067. Western blot analysis of human recombinant Factor H.

Factor H (L20/3) - sc-47686 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor H (L20/3): sc-47686. Western blot analysis of Factor H expression in human PBL whole cell lysate (A) and human recombinant Factor H (B).

Factor H (1H10) - sc-81575 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor H (1H10): sc-81575. Western blot analysis of Factor H expression in human PBL whole cell lysate (A) and human recombinant Factor H (B).

Anti-Factor H [L20/3] antibody (Biotin) - ab191828 from Abcam

Prices $368.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone L20/3

Anti-Factor H [OX23] antibody (Biotin) - ab191992 from Abcam

Prices $368.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone OX23

Anti-Factor H antibody - ab8842 from Abcam

Prices $384.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal
All lanes : Anti-Factor H antibody (ab8842) at 1/500 dilutionLane 1 : Purified Human Factor HLane 2 : Human serum sample (albumin depleted)Lane 3 : Mouse serum sample (albumin depleted)Lane 4 : Rat serum sample (albumin depleted)Lane 5 : Guinea pig serum sample (albumin depleted)Lane 6 : Cattle serum sample (albumin depleted)Lane 7 : Horse serum sample (albumin depleted)Lane 8 : Dog serum sample (albumin depleted)Lane 9 : Cat serum sample (albumin depleted)developed using the ECL techniquePerformed under non-reducing conditions.Image from Bhide MR et al, BMC Res Notes. 2009 Jul 15;2:134, Fig 1.

Anti-Factor H antibody - ab112060 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Factor H antibody (ab112060) at 1 µg/mlLane 1 : Human Plasma Total Protein LysateLane 2 : Lung (Human) Tissue LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Factor H antibody - ab115290 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Formalin-fixed, paraffin-embedded Human liver tissue labelled with ab115290 at 2.5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Factor H antibody - ab36134 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Factor H antibody (ab36134) at 0.03 µg/ml + A431 lysate (RIPA buffer, 30µg total protein per lane)

Anti-Factor H antibody - ab106974 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Factor H antibody (ab106974) at 1/100 dilution + K562 cell line lysate at 35 µg

Anti-Factor H antibody - ab170036 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Factor H antibody (ab170036) at 1/500 dilutionLane 1 : Human fetal lung lysateLane 2 : Human fetal liver lysate

Anti-Factor H antibody - ab134829 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human Liver tissue labelling Factor H with ab134829 at 5 µg/ml.

Anti-Factor H antibody - ab97519 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Factor H antibody (ab97519) at 1/5000 dilution + MOLT4 whole cell lysate at 30 µg

Anti-Factor H antibody - ab61909 from Abcam

Prices $368.00
Sizes 100 µl
Host Chicken
Clonality Polyclonal

Anti-Factor H antibody [63G5] - ab51043 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 63G5
Immunoprecipitation analysis of human plasma using anti-Factor H antibody ab51043, at 1µg for 400µl lysate. Lane 1: human plasma; Lane 2: Immunoprecipitate.

Anti-Factor H antibody [C18/3] - ab121055 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone C18/3

Anti-Factor H antibody [EPR6225] - ab133536 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6225
All lanes : Anti-Factor H antibody [EPR6225] (ab133536) at 1/1000 dilutionLane 1 : Human plasma lysateLane 2 : Human kidney lysateLane 3 : Human fetal lung lysateLane 4 : Human fetal liver lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution
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