Gene Symbol | CFH |
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Entrez Gene | 3075 |
Alt Symbol | AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS |
Species | Human |
Gene Type | protein-coding |
Description | complement factor H |
Other Description | H factor 1 (complement)|H factor 2 (complement)|adrenomedullin binding protein|age-related maculopathy susceptibility 1|beta-1-H-globulin|beta-1H|factor H|factor H-like 1 |
Swissprots | A5PL14 Q5TFM3 P78435 Q2TAZ5 Q14570 Q38G77 Q8N708 Q9NU86 P08603 |
Accessions | AAB01987 ABB02180 AGZ15310 AHH32464 CAA82763 EAW91260 EAW91261 P08603 AI568119 AK225649 AK226113 AK291395 BAF84084 BC012610 BC037285 AAH37285 BC073982 BC110643 AAI10644 BC142699 AAI42700 BM842566 BP324193 JF432152 ADZ15369 M12383 AAA52013 M17517 AAA52016 M65294 AAA35948 X04697 CAB41739 X07523 CAA30403 Y00716 CAA68704 NM_000186 NP_000177 NM_001014975 NP_001014975 |
Function | Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Top Pathways | Complement and coagulation cascades, Staphylococcus aureus infection |
Factor H peptide (577-588) - ab45788 from Abcam
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Human Factor H full length protein - ab131757 from Abcam
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Human Factor H full length protein - ab131758 from Abcam
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Human Factor H full length protein - ab131759 from Abcam
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Human Factor H full length protein - ab167814 from Abcam
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CFH / Complement Factor H Antibody Blocking Peptide - LS-E610 from LifeSpan Bioscience
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CFH / Complement Factor H Antibody Blocking Peptide - LS-E25912 from LifeSpan Bioscience
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FH / Fumarase / MCL Antibody Blocking Peptide - LS-E5848 from LifeSpan Bioscience
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FH / Fumarase / MCL Antibody Blocking Peptide - LS-E26382 from LifeSpan Bioscience
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Fumarase Recombinant Protein - H00002271-P01 from Novus Biologicals
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Recombinant Human Complement Factor H Protein - H00003075-P02 from Novus Biologicals
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Recombinant Human Fumarase Protein - NBC1-18871 from Novus Biologicals
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CFH-Antibody-Center-Blocking-peptide - BP10942c from Abgent, a WuXi AppTec company
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LDL protein - GTX65500 from GeneTex
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Factor H blocking peptide - GTX89512-PEP from GeneTex
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Recombinant Human Complement Factor H (aa 860-1231), CF - 4779-FH-050 from R&D Systems
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NATIVE Human FACTOR H Protein (OPSA11758) - OPSA11758 from Aviva Systems Biology
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Human FH His tag protein - orb84306 from Biorbyt
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Human CFH His tag protein - orb83674 from Biorbyt
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FH Immunizing peptide - orb17264 from Biorbyt
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Factor H - 30C-CP2038U from Fitzgerald
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Fumarase protein - 30R-1246 from Fitzgerald
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Human Complement Factor H Protein - abx066077 from Abbexa
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Factor H Peptide - AC21-0742-P from Abcore
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Complement factor H (CFH) - H00003075-P01 from Acris Antibodies
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