Gzma

Gene Symbol Gzma
Entrez Gene 14938
Alt Symbol AW494114, Ctla-3, Ctla3, Hf, SE1, TSP-1, TSP1
Species Mouse
Gene Type protein-coding
Description granzyme A
Other Description BLT esterase|H factor|Hanukah factor|autocrine thymic lymphoma granzyme-like serine protease|fragmentin-1|serine esterase 1|t cell-specific serine protease 1
Swissprots P11032 P15118
Accessions AAA99897 AAA99898 CAA44426 EDL18394 EDL18395 EDL18396 P11032 AK146132 BAE26923 AK156728 BAE33822 BC061146 AAH61146 M13226 AAA40134 M26183 AAA37735 X14799 CAA32905 NM_010370 NP_034500
Function Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (By similarity). {ECO:0000250}.
Subcellular Location Secreted. Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes.
Tissue Specificity Found in cytotoxic lymphocytes and in normal lymphoid tissues such as thymus and spleen.
Top Pathways Neuroactive ligand-receptor interaction

Granzyme A (GZMA) - P6168 from Acris Antibodies

Category Protein
Prices $840.00
Sizes 100 µg
Species Mouse

Granzyme A (GZMA) - P6170 from Acris Antibodies

Category Protein
Prices $1,010.00
Sizes 100 µg
Species Mouse

Granzyme A (GZMA), Mouse - 20-6875 from ARP American Research Products

Category Protein
Prices $569.00
Sizes 50 µg
Source E.coli
Species Mouse

Recombinant Granzyme A (GZMA) - RPA599Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Granzyme A (GZMA) - RPA599Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Granzyme A(Gzma) - CSB-YP010081MO CSB-EP010081MO CSB-BP010081MO CSB-MP010081MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Granzyme A Protein (Recombinant) - abx167506 from Abbexa

Category Protein
Source Mouse
Species Mouse

Recombinant Mouse GZMA Protein - GZMA-7410M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

Recombinant mouse Granzyme A - CSB-EP010081MO from Cusabio

Category Protein
Source E.coli
Species Mouse

Recombinant Granzyme A (GZMA) - RPU54600 from Biomatik

Category Protein
Prices $200.00, $430.00, $656.00, $820.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg
Source E.coli
Species Mouse

Recombinant Mouse Granzyme A(Gzma) - RPC20502 from Biomatik

Category Protein
Prices $106.00, $242.00, $380.00, $594.00, $945.00, $1,424.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg
Source E.coli
Species Mouse

GZMA Recombinant Protein (OPCD03768) - OPCD03768 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse

Granzyme A (Gzma), Recombinant Protein - MBS951351 from MyBioSource

Category Protein
Prices $190.00, $285.00, $460.00, $750.00, $950.00, $1,170.00, $1,170.00, $1,180.00, $1,400.00, $1,860.00, $1,860.00, $1,860.00, $2,760.00
Sizes 50 µg (E-Coli), 100 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Granzyme A (GZMA), Recombinant Protein - MBS2086779 from MyBioSource

Category Protein
Prices $200.00, $440.00, $690.00
Sizes 10 µg, 50 µg, 100 µg
Source E Coli
Species Mouse

GZMA Recombinant Protein (Mouse) (OPCA05093) - OPCA05093 from Aviva Systems Biology

Category Protein
Species Mouse

Mouse Gzma protein - orb8256 from Biorbyt

Category Protein
Species Mouse
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