Gene Symbol | FCN2 |
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Entrez Gene | 2220 |
Alt Symbol | EBP-37, FCNL, P35, ficolin-2 |
Species | Human |
Gene Type | protein-coding |
Description | ficolin (collagen/fibrinogen domain containing lectin) 2 |
Other Description | 37 kDa elastin-binding protein|L-ficolin|collagen/fibrinogen domain-containing protein 2|ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)|ficolin B|ficolin-2|ficolin-B|ficolin-beta|serum lectin p35 |
Swissprots | Q9UC57 Q15485 A6NFG7 Q6IS69 A8K478 Q7M4P4 |
Accessions | ABB01005 BAA09636 EAW88133 EAW88134 EAW88135 EAW88136 Q15485 AI052239 AK096112 AK290843 BAF83532 AK308476 BC069572 AAH69572 BC069825 AAH69825 BC113935 AAI13936 D49353 BAA08352 JB054537 CCV66758 XM_006717015 XP_006717078 XM_011518392 XP_011516694 NM_004108 NP_004099 NM_015837 NP_056652 NM_015838 NM_015839 |
Function | May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. {ECO:0000269|PubMed:10679061}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
ficolin B (N-12) - sc-55191 from Santa Cruz Biotechnology
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L-ficolin (005-16-1) - sc-80484 from Santa Cruz Biotechnology
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L-ficolin (005-19-1) - sc-80485 from Santa Cruz Biotechnology
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L-ficolin (FCN216) - sc-130296 from Santa Cruz Biotechnology
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L-ficolin (FCN219) - sc-130297 from Santa Cruz Biotechnology
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L-ficolin (G-12) - sc-55242 from Santa Cruz Biotechnology
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L/M-ficolin (H-55) - sc-292239 from Santa Cruz Biotechnology
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Anti-Ficolin 2 antibody - ab118374 from Abcam
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Anti-Ficolin 2 antibody - ab103145 from Abcam
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Anti-Ficolin 2 antibody [19] - ab56225 from Abcam
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Anti-L Ficolin antibody [16] - ab112558 from Abcam
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Anti-FCN2 / Ficolin-2 Antibody - LS-C92524 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody - LS-C66143 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody (clone 11J26) - LS-C182736 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody (clone GN4) - LS-C210264 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody (clone GF1) - LS-C189935 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody (clone GN4, Biotin) - LS-C210265 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody - LS-C310348 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody (clone GN5) - LS-C210269 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody - LS-C310349 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody (aa71-120) - LS-C110672 from LifeSpan Bioscience
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Anti-FCN2 / Ficolin-2 Antibody (aa97-254) - LS-C293939 from LifeSpan Bioscience
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Ficolin-2 Antibody (297018) - MAB2428 from Novus Biologicals
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Ficolin-2 Antibody - AF2428 from Novus Biologicals
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Ficolin-2 Antibody - 24460002 from Novus Biologicals
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