| Gene Symbol |
FCN2
|
| Entrez Gene |
2220
|
| Alt Symbol |
EBP-37, FCNL, P35, ficolin-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ficolin (collagen/fibrinogen domain containing lectin) 2
|
| Other Description |
37 kDa elastin-binding protein|L-ficolin|collagen/fibrinogen domain-containing protein 2|ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)|ficolin B|ficolin-2|ficolin-B|ficolin-beta|serum lectin p35
|
| Swissprots |
Q9UC57 Q15485 A6NFG7 Q6IS69 A8K478 Q7M4P4
|
| Accessions |
ABB01005 BAA09636 EAW88133 EAW88134 EAW88135 EAW88136 Q15485 AI052239 AK096112 AK290843 BAF83532 AK308476 BC069572 AAH69572 BC069825 AAH69825 BC113935 AAI13936 D49353 BAA08352 JB054537 CCV66758 XM_006717015 XP_006717078 XM_011518392 XP_011516694 NM_004108 NP_004099 NM_015837 NP_056652 NM_015838 NM_015839
|
| Function |
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. {ECO:0000269|PubMed:10679061}.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Expressed by the liver and secreted in plasma.
|