Gene Symbol | RABAC1 |
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Entrez Gene | 10567 |
Alt Symbol | PRA1, PRAF1, YIP3 |
Species | Human |
Gene Type | protein-coding |
Description | Rab acceptor 1 (prenylated) |
Other Description | PRA1 domain family 1|PRA1 family protein 1|prenylated Rab acceptor 1|prenylated Rab acceptor protein 1 |
Swissprots | Q9UI14 Q7Z4Y2 Q9Y3R1 |
Accessions | EAW57086 EAW57087 EAW57088 Q9UI14 AF112202 AAF17190 AF112996 AAP97229 AI376198 AJ133534 CAB43107 BC008950 AAH08950 BT019964 AAV38767 CF242972 CR457214 CAG33495 CR542116 CAG46913 DB454056 NM_006423 NP_006414 |
Function | General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Note=According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles. {ECO:0000250}. |
Tissue Specificity | Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach. {ECO:0000269|PubMed:11520070}. |
PRA1 (G-13) - sc-162033 from Santa Cruz Biotechnology
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PRA1 (P-17) - sc-162035 from Santa Cruz Biotechnology
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Anti-PRA1 antibody - ab124343 from Abcam
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Anti-PRA1 antibody [EPR1747Y] - ab76413 from Abcam
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Anti-RABAC1 Antibody (aa1-185) - LS-C178916 from LifeSpan Bioscience
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Anti-RABAC1 Antibody (C-Terminus, clone EPR1747Y) - LS-C50085 from LifeSpan Bioscience
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PRA1 Antibody - NBP1-80883 from Novus Biologicals
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PRA1 Antibody (EPR1747Y) - NB100-80034 from Novus Biologicals
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PRA1 Antibody (2A4) - H00010567-M01 from Novus Biologicals
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Anti-RABAC1 antibody produced in rabbit - HPA029171 from Sigma-Aldrich
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Monoclonal Anti-RABAC1, (N-terminal) antibody produced in mouse - SAB1402523 from Sigma-Aldrich
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Anti-RABAC1 (2-15) antibody produced in rabbit - SAB1100930 from Sigma-Aldrich
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PRA1-Antibody-C-term - AJ1647a from Abgent, a WuXi AppTec company
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RABAC1 antibody - orb78167 from Biorbyt
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RABAC1 antibody - 70R-19728 from Fitzgerald
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RABAC1 Polyclonal Antibody - A4435 from ABclonal
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RABAC1 Antibody - abx036306 from Abbexa
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RABAC1 Antibody - abx003314 from Abbexa
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RABAC1 antibody - 10542-1-AP from Acris Antibodies
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RABAC1 antibody - H00010567-M01 from Acris Antibodies
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Anti-RABAC1, Polyclonal Antibody - 25-A4435 from ARP American Research Products
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RABAC1 antibody - STJ25270 from St John's Laboratory Ltd
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RABAC1 antibody - 10542-1-AP from Proteintech Group
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RABAC1 - A4435 from NeoScientific
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RABAC1 Antibody - 39743 from Signalway Antibody
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