| Gene Symbol |
RABAC1
|
| Entrez Gene |
10567
|
| Alt Symbol |
PRA1, PRAF1, YIP3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rab acceptor 1 (prenylated)
|
| Other Description |
PRA1 domain family 1|PRA1 family protein 1|prenylated Rab acceptor 1|prenylated Rab acceptor protein 1
|
| Swissprots |
Q9UI14 Q7Z4Y2 Q9Y3R1
|
| Accessions |
EAW57086 EAW57087 EAW57088 Q9UI14 AF112202 AAF17190 AF112996 AAP97229 AI376198 AJ133534 CAB43107 BC008950 AAH08950 BT019964 AAV38767 CF242972 CR457214 CAG33495 CR542116 CAG46913 DB454056 NM_006423 NP_006414
|
| Function |
General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Note=According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles. {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach. {ECO:0000269|PubMed:11520070}.
|
![Western Blot: PRA1 Overexpression Lysate (Adult Normal) [NBL1-15094] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PRA1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4747_PRA1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15094-img0002.jpg)