YWHAB

Gene Symbol	YWHAB
Entrez Gene	7529
Alt Symbol	GW128, HEL-S-1, HS1, KCIP-1, YWHAA
Species	Human
Gene Type	protein-coding
Description	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
Other Description	14-3-3 alpha|14-3-3 protein beta/alpha|brain protein 14-3-3, beta isoform|epididymis secretory protein Li 1|protein 1054|protein kinase C inhibitor protein 1|protein kinase C inhibitor protein-1|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Swissprots	E1P616 A8K9K2 P31946
Accessions	EAW75893 EAW75894 EAW75895 EAW75896 P31946 AA845374 AB209759 BAD92996 AB451260 BAG70074 AB451386 BAG70200 AF064847 AF107406 AAD44524 AK292717 BAF85406 AL834170 BC001359 AAH01359 BC010352 BF316820 DB443535 EU794580 ACJ13634 EU832334 ACE87591 EU832419 ACE86904 X57346 CAA40621 NM_003404 NP_003395 NM_139323 NP_647539
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. {ECO:0000269|PubMed:17717073, ECO:0000269|PubMed:19592491}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Cell cycle, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human 14-3-3 alpha + beta full length protein - ab85273 from Abcam Category Protein Prices $188.00 Sizes 20 µg Source E. coli Species Human

Human 14-3-3 alpha + beta full length protein - ab55727 from Abcam Category Protein Prices $235.00 Sizes 20 µg Source E. coli Species Human

Human 14-3-3 beta full length protein - ab78683 from Abcam Category Protein Prices $188.00 Sizes 50 µg Source E. coli Species Human

Human 14-3-3 beta full length protein - ab82735 from Abcam Category Protein Prices $188.00 Sizes 500 µg Source E. coli Species Human

YWHAB / 14-3-3 Beta Antibody Blocking Peptide - LS-E10667 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

YWHAB / 14-3-3 Beta Antibody Blocking Peptide - LS-E9543 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human 14-3-3 beta/alpha Protein - NBC1-18405 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Species Human

14-3-3 beta/alpha Recombinant Protein - H00007529-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

14-3-3 beta/alpha Peptide - P3190 from Novus Biologicals Category Peptide Species Human

14-3-3 beta/alpha Peptide - P3189 from Novus Biologicals Category Peptide Species Human

YWHAB-Antibody-C-term-Blocking-peptide - BP8155b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

YWHAB-Antibody-N-term-Blocking-peptide - BP8155a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

YWHAB Protein (OPPA01701) - OPPA01701 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human YWHAB protein - orb83501 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source E. coli Species Human

Cynomolgus YWHAB protein - orb139887 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli

Human YWHAB GST tag protein - orb83493 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source E. coli Species Human

Human YWHAB protein - orb80879 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Species Human

Human YWHAB protein - orb245088 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

YWHAB Blocking Peptide - 33R-6929 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

14-3-3 protein beta/alpha (1-246) - AR09099PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 500 µg Source E. coli Species Human

14-3-3 protein beta/alpha (1-246) - AR09099PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 100 µg Source E. coli Species Human

14-3-3 protein beta/alpha - H00007529-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

14-3-3 protein beta/alpha - H00007529-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Tyr-3/Trp- 5 Monooxygenase Activation Protein Beta, Human Recombinant - 228-10001-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human YWHAB - 228-10001-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

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