Gene Symbol | ZFHX3 |
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Entrez Gene | 463 |
Alt Symbol | ATBF1, ATBT, ZNF927 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger homeobox 3 |
Other Description | AT motif-binding factor 1|AT-binding transcription factor 1|ZFH-3|alpha-fetoprotein enhancer binding protein|alpha-fetoprotein enhancer-binding protein|zinc finger homeobox protein 3|zinc finger homeodomain protein 3 |
Swissprots | O15101 Q13719 D3DWS8 Q15911 |
Accessions | AAC31674 AAC79153 AAR26475 EAW59168 EAW59169 EAW59170 Q15911 BC029653 AAH29653 BC043190 D10250 BAA01095 L32832 AAC14462 L32833 AAC37582 XM_005255957 XP_005256014 NM_001164766 NP_001158238 NM_006885 NP_008816 |
Function | Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down- regulates the MUC5AC promoter in gastric cancer. {ECO:0000269|PubMed:11312261, ECO:0000269|PubMed:17330845}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Not found in normal gastric mucosa but found in gastric carcinoma cells (at protein level). {ECO:0000269|PubMed:17330845}. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
ATBF1 (C-15) - sc-21044 from Santa Cruz Biotechnology
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ATBF1 (G-13) - sc-21162 from Santa Cruz Biotechnology
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ATBF1 (H-150) - sc-48807 from Santa Cruz Biotechnology
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ATBF1-A (I-19) - sc-21160 from Santa Cruz Biotechnology
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ATBF1-A (Q-20) - sc-21161 from Santa Cruz Biotechnology
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Anti-ATBF1 antibody - ab119909 from Abcam
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Anti-ATBF1 antibody - ab54853 from Abcam
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Anti-ZFHX3 / ATBF1 Antibody (aa761-810) - LS-C119078 from LifeSpan Bioscience
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Anti-ZFHX3 / ATBF1 Antibody (aa517-787) IHC-plus⢠- LS-B10493 from LifeSpan Bioscience
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Anti-ZFHX3 / ATBF1 Antibody - LS-C179898 from LifeSpan Bioscience
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Anti-ZFHX3 / ATBF1 Antibody (clone 3B1) - LS-C196706 from LifeSpan Bioscience
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Anti-ZFHX3 / ATBF1 Antibody - LS-C179897 from LifeSpan Bioscience
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ATBF1/ZFHX3 Antibody - AF7384 from Novus Biologicals
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ATBF1/ZFHX3 Antibody - NBP2-34126 from Novus Biologicals
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ATBF1/ZFHX3 Antibody (3B1) - H00000463-M01 from Novus Biologicals
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ATBF1/ZFHX3 Antibody - H00000463-A01 from Novus Biologicals
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ATBF1 Polyclonal Antibody - bs-11805R from Bioss
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ATBF1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11805R-A350 from Bioss
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ATBF1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11805R-A488 from Bioss
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ATBF1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11805R-A555 from Bioss
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ATBF1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11805R-A647 from Bioss
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ATBF1 Polyclonal Antibody, Cy3 Conjugated - bs-11805R-Cy3 from Bioss
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ATBF1 Polyclonal Antibody, Cy5 Conjugated - bs-11805R-Cy5 from Bioss
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ATBF1 Polyclonal Antibody, Cy5.5 Conjugated - bs-11805R-Cy5.5 from Bioss
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ATBF1 Polyclonal Antibody, Cy7 Conjugated - bs-11805R-Cy7 from Bioss
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