Gene Symbol | ZFHX3 |
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Entrez Gene | 463 |
Alt Symbol | ATBF1, ATBT, ZNF927 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger homeobox 3 |
Other Description | AT motif-binding factor 1|AT-binding transcription factor 1|ZFH-3|alpha-fetoprotein enhancer binding protein|alpha-fetoprotein enhancer-binding protein|zinc finger homeobox protein 3|zinc finger homeodomain protein 3 |
Swissprots | O15101 Q13719 D3DWS8 Q15911 |
Accessions | AAC31674 AAC79153 AAR26475 EAW59168 EAW59169 EAW59170 Q15911 BC029653 AAH29653 BC043190 D10250 BAA01095 L32832 AAC14462 L32833 AAC37582 XM_005255957 XP_005256014 NM_001164766 NP_001158238 NM_006885 NP_008816 |
Function | Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down- regulates the MUC5AC promoter in gastric cancer. {ECO:0000269|PubMed:11312261, ECO:0000269|PubMed:17330845}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Not found in normal gastric mucosa but found in gastric carcinoma cells (at protein level). {ECO:0000269|PubMed:17330845}. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
Zinc finger homeobox protein 3, ZFHX3, Human, ELISA Kit - E1065h from ARP American Research Products
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zinc finger homeobox 3, ELISA Kit - MBS9340156 from MyBioSource
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Zinc finger homeobox protein 3, ELISA Kit - MBS280797 from MyBioSource
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Zinc Finger Homeobox Protein 3 (ZFHX3), ELISA Kit - MBS9301451 from MyBioSource
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Mouse ZFHX3 / ATBF1 ELISA Kit (Custom ELISA) - LS-F15861 from LifeSpan Bioscience
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Human ZFHX3 / ATBF1 ELISA Kit (Custom ELISA) - LS-F15862 from LifeSpan Bioscience
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ZFHX3 - EKH2404 from Nordic BioSite
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Human ZFHX3 ELISA Kit - E040909 from Biobool
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ZFHX3 ELISA Kit (Human) (OKEH04430) - OKEH04430 from Aviva Systems Biology
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Zinc finger homeobox protein 3, ELISA Kit - MBS760989 from MyBioSource
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Zinc finger homeobox protein 3, ELISA Kit - MBS2881762 from MyBioSource
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Human ZFHX3 / ATBF1 ELISA Kit (Sandwich ELISA) - LS-F33839 from LifeSpan Bioscience
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