Gene Symbol | CYP4A22 |
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Entrez Gene | 284541 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 4, subfamily A, polypeptide 22 |
Other Description | CYPIVA22|cytochrome P450 4A22|cytochrome P450 4A22K|fatty acid omega-hydroxylase|lauric acid omega-hydroxylase |
Swissprots | Q9NRM4 Q6JXK7 Q5TCH3 Q6JXK8 Q5TCH4 |
Accessions | AAF76722 CAI19736 CAI19737 CAI19738 Q5TCH4 AY280371 AAQ21367 AY280372 AAQ21368 BC142607 AAI42608 BC142690 AAI42691 BC148248 AAI48249 XM_005270767 XP_005270824 XM_005270768 XP_005270825 XM_005270769 XP_005270826 XM_005270770 XP_005270827 NM_001010969 NP_001010969 NM_001308102 NP_001295031 |
Function | Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Shows no activity towards arachidonic acid and prostaglandin A1. Lacks functional activity in the kidney and does not contribute to renal 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis. {ECO:0000269|PubMed:10860550, ECO:0000269|PubMed:15611369}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
Top Pathways | Vascular smooth muscle contraction, Fatty acid degradation |
CYP4A22 (I-11) - sc-131486 from Santa Cruz Biotechnology
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CYP4A22 (S-19) - sc-101930 from Santa Cruz Biotechnology
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Anti-Cytochrome P450 4A22 antibody - ab59125 from Abcam
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Anti-Cytochrome P450 4A22 antibody - ab98035 from Abcam
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Anti-Cytochrome P450 4A22 antibody - N-terminal - ab179668 from Abcam
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Anti-CYPIVA22 / CYP4A22 Antibody (N-Terminus) - LS-C30534 from LifeSpan Bioscience
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Anti-CYPIVA22 / CYP4A22 Antibody (N-Terminus) - LS-C201404 from LifeSpan Bioscience
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Anti-CYPIVA22 / CYP4A22 Antibody (aa35-84) - LS-C107633 from LifeSpan Bioscience
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CYP4A22 Antibody - NBP1-80495 from Novus Biologicals
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CYP4A22 Antibody - NBP1-80496 from Novus Biologicals
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CYP4A11/22 Polyclonal Antibody - bs-5055R from Bioss
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Anti-CYP4A22 antibody produced in rabbit - AV41861 from Sigma-Aldrich
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Anti-CYP4A22, (N-terminal) antibody produced in rabbit - SAB2104824 from Sigma-Aldrich
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CYP4A22 Antibody - N-terminal region (ARP41812_P050) - ARP41812_P050 from Aviva Systems Biology
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CYP4A22 antibody - N-terminal region (ARP41861_P050) - ARP41861_P050 from Aviva Systems Biology
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CYP4A22 antibody - N-terminal region (ARP41862_P050) - ARP41862_P050 from Aviva Systems Biology
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CYP4A22 antibody, N-term - GTX47104 from GeneTex
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CYP4A22 antibody, N-term - GTX47105 from GeneTex
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CYP4A22 antibody - 70R-6524 from Fitzgerald
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CYP4A22 antibody - 70R-7014 from Fitzgerald
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CYP4A22 Antibody - 29-654 from ProSci
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CYP4A22 Antibody - GWB-MN972I from Genway Biotech
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CYP4A22 Antibody - GWB-MN973A from Genway Biotech
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Anti-CYP4A22 (aa 1-50) polyclonal antibody - DPABH-13117 from Creative Diagnostics
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CYP4A11/22 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-5055R-A350 from Bioss
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