Gene Symbol | ACY3 |
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Entrez Gene | 91703 |
Alt Symbol | ACY-3, HCBP1 |
Species | Human |
Gene Type | protein-coding |
Description | aminoacylase 3 |
Other Description | HCV core-binding protein 1|N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)|acylase III|aminoacylase-3|aspartoacylase (aminoacylase) 3|aspartoacylase (aminocyclase) 3|aspartoacylase-2|hepatitis C virus core-binding protein 1 |
Swissprots | Q96HD9 |
Accessions | EAW74663 EAW74664 Q96HD9 AF359506 AAM00248 AK308710 AY032593 AAK51135 AY040761 AAK94770 AY169233 AAN87896 BC008689 AAH08689 HQ447856 ADQ32340 XM_011545349 XP_011543651 XM_011545350 XP_011543652 XM_011545351 XP_011543653 NM_080658 NP_542389 |
Function | Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity). {ECO:0000250}. |
Subcellular Location | Apical cell membrane {ECO:0000269|PubMed:19486448}; Peripheral membrane protein {ECO:0000269|PubMed:19486448}. Cytoplasm {ECO:0000269|PubMed:19486448}. Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm. |
Aspartoacylase-2 (ACY3), Human, ELISA Kit - E01A1236 from ARP American Research Products
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aspartoacylase (aminocyclase) 3, ELISA Kit - MBS9324722 from MyBioSource
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Human ACY3 ELISA Kit - E074600 from Biobool
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