| Gene Symbol |
ACY3
|
| Entrez Gene |
91703
|
| Alt Symbol |
ACY-3, HCBP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
aminoacylase 3
|
| Other Description |
HCV core-binding protein 1|N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)|acylase III|aminoacylase-3|aspartoacylase (aminoacylase) 3|aspartoacylase (aminocyclase) 3|aspartoacylase-2|hepatitis C virus core-binding protein 1
|
| Swissprots |
Q96HD9
|
| Accessions |
EAW74663 EAW74664 Q96HD9 AF359506 AAM00248 AK308710 AY032593 AAK51135 AY040761 AAK94770 AY169233 AAN87896 BC008689 AAH08689 HQ447856 ADQ32340 XM_011545349 XP_011543651 XM_011545350 XP_011543652 XM_011545351 XP_011543653 NM_080658 NP_542389
|
| Function |
Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Apical cell membrane {ECO:0000269|PubMed:19486448}; Peripheral membrane protein {ECO:0000269|PubMed:19486448}. Cytoplasm {ECO:0000269|PubMed:19486448}. Note=Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm.
|