DPYD

Gene Symbol DPYD
Entrez Gene 1806
Alt Symbol DHP, DHPDHASE, DPD
Species Human
Gene Type protein-coding
Description dihydropyrimidine dehydrogenase
Other Description dihydropyrimidine dehydrogenase [NADP(+)]|dihydrothymine dehydrogenase|dihydrouracil dehydrogenase
Swissprots Q96TH1 Q16761 A8K5A2 Q16694 E9PFN1 Q32NB0 A2RRQ3 B1AN21 Q96HL6 Q12882 A8MWG9 A2RRQ2
Accessions AAB07049 BAD35129 CAA64973 EAW73002 EAW73003 Q12882 AB003063 BAA89789 AI124948 AK291217 BAF83906 AK297515 BAG59923 BC008379 AAH08379 BC064027 AAH64027 BC108742 AAI08743 BC131777 AAI31778 BC131778 AAI31779 BT006740 AAP35386 DA721123 U09178 AAA57474 U20938 AAB51366 XM_005270562 XP_005270619 XM_006710397 XP_006710460 NM_000110 NP_000101 NM_001160301 NP_001153773
Function Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
Subcellular Location Cytoplasm.
Tissue Specificity Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
Top Pathways Drug metabolism - other enzymes, Pyrimidine metabolism, beta-Alanine metabolism, Pantothenate and CoA biosynthesis

DPYD (D35A8) Rabbit mAb - 4654 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D35A8
Western blot analysis of extracts from HeLa and IGROV-1 cells using DPYD (D35A8) Rabbit mAb.

DPYD (A-5) - sc-376712 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DPYD (A-5): sc-376712. Western blot analysis of DPYD expression in HeLa whole cell lysate.

DPYD (C-14) - sc-34065 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DPYD (C-14): sc-34065. Western blot analysis of DPYD expression in Hep G2 (A), HL-60 (B), COLO 320DM (C) and HeLa (D) whole cell lysates.

DPYD (D-8) - sc-271308 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DPYD (D-8): sc-271308. Western blot analysis of DPYD expression in HeLa whole cell lysate.

DPYD (F-8) - sc-376681 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DPYD (F-8): sc-376681. Western blot analysis of DPYD expression in HeLa whole cell lysate.

DPYD (E-13) - sc-34063 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DPYD (G-16) - sc-34064 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DPYD (G-16): sc-34064. Western blot analysis of DPYD expression in non-transfected: sc-117752 (A) and human DPYD transfected: sc-112124 (B) 293T whole cell lysates.

DPYD (H-300) - sc-50521 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DPYD (H-300): sc-50521. Western blot analysis of DPYD expression in non-transfected 293T: sc-117752 (A), human DPYD transfected 293T: sc-117303 (B) and HeLa (C) whole cell lysates.

Anti-DPYD antibody - ab54797 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DPYD antibody - ab180609 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse lung tissue labelling DPYD with ab180609 at 1/100. Magnification: 200x.

Anti-DPYD antibody - ab190616 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DPYD antibody (ab190616) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-DPYD antibody [EPR8811] - ab134922 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8811
All lanes : Anti-DPYD antibody [EPR8811] (ab134922) at 1/1000 dilutionLane 1 : Fetal kidney cell lysateLane 2 : THP1 cell lysateLane 3 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilutiondeveloped using the ECL technique

Anti-DPYD / DPD Antibody - LS-C335165 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded mouse lung using DPYD antibody at dilution of 1:100 (200x lens).

Anti-DPYD / DPD Antibody (N-Terminus) - LS-C128610 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-DPYD / DPD Antibody (aa1-111, clone 10C16, Azide-free) - LS-C183558 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10C16

Anti-DPYD / DPD Antibody - LS-C193016 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot.

Anti-DPYD Antibody (Internal, clone EPR8811) - LS-C154696 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8811
IHC of paraffin-embedded human lung tissue using anti-DPYD antibody.

Anti-DPYD / DPD Antibody (aa33-52) - LS-C312908 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of DPYD / DPD antibody. All lanes: Anti-DPYD at 0.5ug/ml. WB: MM231 Whole Cell Lysate at 40ug. Predicted bind size: 111KD. Observed bind size: 111KD.

Anti-DPYD / DPD Antibody (aa1-174) - LS-C186323 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
DPYD antibody [N1N2], N-term detects DPYD protein at cytoplasm on H358 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H358 xenograft. DPYD antibody [N1N2], N-term dilution:1:500.

Anti-DPYD / DPD Antibody (clone 7D4) - LS-C197076 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7D4
Immunofluorescence of monoclonal antibody to DPYD on HeLa cell. [antibody concentration 10 ug/ml]

DPYD Antibody (7D4) - H00001806-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7D4
Western Blot: DPYD Antibody (7D4) [H00001806-M01] - DPYD monoclonal antibody (M01), clone 7D4 Analysis of DPYD expression in HeLa.

DPYD Antibody - NBP2-37911 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: DPYD Antibody [NBP2-37911] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuronal cells.

DPYD Polyclonal Antibody - bs-8288R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DPYD antibody produced in rabbit - SAB4300722 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-DPYD antibody produced in mouse - WH0001806M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7D4
<B>Immunoblotting</B><BR/>Monoclonal Anti-DPYD, <B>Cat. No. WH0001806M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~111.3 kDa using HeLa lysate.
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