| Gene Symbol |
PRSS2
|
| Entrez Gene |
5645
|
| Alt Symbol |
TRY2, TRY8, TRYP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protease, serine, 2 (trypsin 2)
|
| Other Description |
anionic trypsinogen|protease serine 2 preproprotein|trypsin II|trypsin-2|trypsinogen 2
|
| Swissprots |
P07478
|
| Accessions |
AAC13351 AAC80209 EAL23774 EAW51922 EAW51923 EAW51924 P07478 BC005814 AAH05814 BC030260 BC103997 AAI03998 BC103998 AAI03999 BC107784 AAI07785 BQ786948 CA867206 CA951033 DQ846872 ABI63359 DQ846873 ABI63360 DQ891044 ABM81970 DQ894223 ABM85149 M27602 AAA61232 NM_001303414 NP_001290343 NM_002770 NP_002761 NR_130149
|
| Function |
In the ileum, may be involved in defensin processing, including DEFA5. {ECO:0000269|PubMed:12021776}.
|
| Subcellular Location |
Secreted, extracellular space.
|
| Tissue Specificity |
Expressed in Paneth cells, at the base of small intestinal crypts. {ECO:0000269|PubMed:12021776}.
|
| Top Pathways |
Protein digestion and absorption, Pancreatic secretion, Influenza A, Neuroactive ligand-receptor interaction
|
![Western Blot: PRSS2 Lysate [NBL1-14842] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for PRSS2](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8928_PRSS2%2520Lysate-Western%2520Blot-NBL1-14842-img0001.jpg)