Gene Symbol | PRSS2 |
---|---|
Entrez Gene | 5645 |
Alt Symbol | TRY2, TRY8, TRYP2 |
Species | Human |
Gene Type | protein-coding |
Description | protease, serine, 2 (trypsin 2) |
Other Description | anionic trypsinogen|protease serine 2 preproprotein|trypsin II|trypsin-2|trypsinogen 2 |
Swissprots | P07478 |
Accessions | AAC13351 AAC80209 EAL23774 EAW51922 EAW51923 EAW51924 P07478 BC005814 AAH05814 BC030260 BC103997 AAI03998 BC103998 AAI03999 BC107784 AAI07785 BQ786948 CA867206 CA951033 DQ846872 ABI63359 DQ846873 ABI63360 DQ891044 ABM81970 DQ894223 ABM85149 M27602 AAA61232 NM_001303414 NP_001290343 NM_002770 NP_002761 NR_130149 |
Function | In the ileum, may be involved in defensin processing, including DEFA5. {ECO:0000269|PubMed:12021776}. |
Subcellular Location | Secreted, extracellular space. |
Tissue Specificity | Expressed in Paneth cells, at the base of small intestinal crypts. {ECO:0000269|PubMed:12021776}. |
Top Pathways | Protein digestion and absorption, Pancreatic secretion, Influenza A, Neuroactive ligand-receptor interaction |