Gene Symbol | PRSS2 |
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Entrez Gene | 5645 |
Alt Symbol | TRY2, TRY8, TRYP2 |
Species | Human |
Gene Type | protein-coding |
Description | protease, serine, 2 (trypsin 2) |
Other Description | anionic trypsinogen|protease serine 2 preproprotein|trypsin II|trypsin-2|trypsinogen 2 |
Swissprots | P07478 |
Accessions | AAC13351 AAC80209 EAL23774 EAW51922 EAW51923 EAW51924 P07478 BC005814 AAH05814 BC030260 BC103997 AAI03998 BC103998 AAI03999 BC107784 AAI07785 BQ786948 CA867206 CA951033 DQ846872 ABI63359 DQ846873 ABI63360 DQ891044 ABM81970 DQ894223 ABM85149 M27602 AAA61232 NM_001303414 NP_001290343 NM_002770 NP_002761 NR_130149 |
Function | In the ileum, may be involved in defensin processing, including DEFA5. {ECO:0000269|PubMed:12021776}. |
Subcellular Location | Secreted, extracellular space. |
Tissue Specificity | Expressed in Paneth cells, at the base of small intestinal crypts. {ECO:0000269|PubMed:12021776}. |
Top Pathways | Protein digestion and absorption, Pancreatic secretion, Influenza A, Neuroactive ligand-receptor interaction |
Trypsin-2 CRISPR/Cas9 KO Plasmid (h) - sc-417139 from Santa Cruz Biotechnology
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Trypsin-2 HDR Plasmid (h) - sc-417139-HDR from Santa Cruz Biotechnology
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Trypsin-2 Double Nickase Plasmid (h) - sc-417139-NIC from Santa Cruz Biotechnology
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Trypsin-2 Double Nickase Plasmid (h2) - sc-417139-NIC-2 from Santa Cruz Biotechnology
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Trypsin-2 CRISPR Activation Plasmid (h) - sc-417139-ACT from Santa Cruz Biotechnology
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Trypsin-2 CRISPR Activation Plasmid (h2) - sc-417139-ACT-2 from Santa Cruz Biotechnology
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Trypsin-2 Lentiviral Activation Particles (h) - sc-417139-LAC from Santa Cruz Biotechnology
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Trypsin-2 Lentiviral Activation Particles (h2) - sc-417139-LAC-2 from Santa Cruz Biotechnology
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Trypsin-2 siRNA (h) - sc-106645 from Santa Cruz Biotechnology
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Trypsin-2 shRNA Plasmid (h) - sc-106645-SH from Santa Cruz Biotechnology
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Trypsin-2 shRNA (h) Lentiviral Particles - sc-106645-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU118341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17531 from Sigma-Aldrich
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PRSS2 siRNA (Human) - CRH3804 from Cohesion Biosciences
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Trypsin 2/PRSS2 RNAi - H00005645-R01 from Novus Biologicals
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shRNA set against Human PRSS2(NM_002770.2) - SHR144670 from Creative biogene
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Human PRSS2 siRNA - orb264306 from Biorbyt
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PRSS2 shRNA Plasmid (Human) - CHH3804 from Cohesion Biosciences
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PRSS2 miRNA 3'UTR clone - MiUTR1H-08337 from Creative biogene
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