HSPB1

Gene Symbol	HSPB1
Entrez Gene	3315
Alt Symbol	CMT2F, HEL-S-102, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27
Species	Human
Gene Type	protein-coding
Description	heat shock 27kDa protein 1
Other Description	28 kDa heat shock protein|HSP 27|epididymis secretory protein Li 102|estrogen-regulated 24 kDa protein|heat shock 27 kDa protein|heat shock 27kD protein 1|heat shock protein beta-1|stress-responsive protein 27
Swissprots	Q6FI47 Q96EI7 Q9UC35 Q96C20 B2R4N8 Q9UC36 Q9UC31 P04792 Q9UC34
Accessions	AAA62175 ABC88475 CDM22284 EAW71803 P04792 AB020027 BAB17232 AF086135 AK296890 BAG59449 AK311446 AK311894 BAG34835 AL050380 BC000510 AAH00510 BC012292 AAH12292 BC012768 AAH12768 BC014920 AAH14920 BC073768 AAH73768 BP231480 BT019888 AAV38691 CR407614 CAG28542 CR536489 CAG38728 DQ891304 ABM82230 DQ893349 ABM84275 DQ894489 ABM85415 DQ896669 ABM87668 FJ224323 ACI46015 S74571 AAB20722 U90906 AAB51056 X16477 CAA34498 X54079 CAA38016 NM_001540 NP_001531
Function	Involved in stress resistance and actin organization.
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Tissue Specificity	Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle. {ECO:0000269|PubMed:1560006}.
Top Pathways	VEGF signaling pathway, MAPK signaling pathway, Amoebiasis, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PathScan ® Phospho-HSP27 (Ser82) Sandwich ELISA Kit - 7152 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan ® Phospho-HSP27 (Ser78) Sandwich ELISA Kit - 7290 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan ® Total HSP27 Sandwich ELISA Kit - 7295 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

Heat Shock Protein 27 (HSP27) Human ELISA Kit - ab108862 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity > 0.3 ng/ml Range 0.313 ng/ml - 80 ng/ml

Heat Shock Protein 27 (HSP27) Human ELISA Kit - ab113334 from Abcam Category ELISA Kit Prices $499.00 Sizes 1 x 96 tests Sensitivity < 0.15 ng/ml Range 0.205 ng/ml - 50 ng/ml

Heat Shock Protein 27 (HSP27) Human SimpleStep ELISA™ Kit - ab193757 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 62.3 pg/ml Range 469 pg/ml - 30000 pg/ml

Human HSPB1 / HSP27 ELISA Kit (Sandwich ELISA) - LS-F2736 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 5 pg/ml Range 0.205-20 ng/ml

Human HSPB1 / HSP27 ELISA Kit (Sandwich ELISA) - LS-F4523 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.28 ng/ml Range 0.205-20 ng/ml

Rat HSPB1 / HSP27 ELISA Kit (Sandwich ELISA) - LS-F4524 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.26 ng/ml Range 0.205-20 ng/ml

Mouse HSPB1 / HSP27 ELISA Kit (Sandwich ELISA) - LS-F4525 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.33 ng/ml Range 0.205-20 ng/ml

Bovine HSPB1 / HSP27 ELISA Kit (Sandwich ELISA) - LS-F5823 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.272 ng/ml Range 0.205-20 ng/ml

Human HSPB1 / HSP27 ELISA Kit (Sandwich ELISA) - LS-F450 from LifeSpan Bioscience Category ELISA Kit Prices $620.00, $1,090.00, $2,380.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.205 ng/ml Range 0.205-20 ng/ml

Mouse/Human/Rat HSPB1 / HSP27 ELISA Kit (Cell-Based ELISA) - LS-F2063 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.205-20 ng/ml

Human Phospho-HSPB1 / HSP27 (Ser15) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1532 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.205-20 ng/ml

Human Phospho-HSPB1 / HSP27 (Ser78) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1533 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.205-20 ng/ml

Mouse/Human/Rat Phospho-HSPB1 / HSP27 (Ser82) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1534 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.205-20 ng/ml

Rat HSPB1 / HSP27 ELISA Kit (Sandwich ELISA) - LS-F11672 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.205-20 ng/ml

Human Heat Shock Protein 27 ELISA Kit - RAB0217 from Sigma-Aldrich Category ELISA Kit Prices $608.00 Sizes 1 kt

Human Total HSP27 DuoSet IC Economy Pack, 15 Plate - DYC1580E from R&D Systems Category ELISA Kit

Human Total HSP27 DuoSet IC ELISA - DYC1580-2 from R&D Systems Category ELISA Kit Prices $329.00, $649.00, $1,425.00 Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates), 1 pack (for 15 Plates) Range 31.20 - 2,000 pg/mL

Human Total HSP27 DuoSet IC, 5 Plate - DYC1580-5 from R&D Systems Category ELISA Kit

Phospho-HSP27 (S78/S82) DuoSet IC ELISA - DYC2314-2 from R&D Systems Category ELISA Kit Prices $329.00, $649.00 Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates) Range 62.50 - 4,000 pg/mL

Phospho-HSP27 (S78/S82) DuoSet IC, 5 Plate - DYC2314-5 from R&D Systems Category ELISA Kit

Human HSP27 DuoSet ELISA - DY1580 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Human HSPB1 ELISA Kit - abx151867 from Abbexa Category ELISA Kit Sensitivity 0.27 ng/ml Range 0.781 ng/ml - 50 ng/ml

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