HSPB1

Gene Symbol	HSPB1
Entrez Gene	3315
Alt Symbol	CMT2F, HEL-S-102, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27
Species	Human
Gene Type	protein-coding
Description	heat shock 27kDa protein 1
Other Description	28 kDa heat shock protein|HSP 27|epididymis secretory protein Li 102|estrogen-regulated 24 kDa protein|heat shock 27 kDa protein|heat shock 27kD protein 1|heat shock protein beta-1|stress-responsive protein 27
Swissprots	Q6FI47 Q96EI7 Q9UC35 Q96C20 B2R4N8 Q9UC36 Q9UC31 P04792 Q9UC34
Accessions	AAA62175 ABC88475 CDM22284 EAW71803 P04792 AB020027 BAB17232 AF086135 AK296890 BAG59449 AK311446 AK311894 BAG34835 AL050380 BC000510 AAH00510 BC012292 AAH12292 BC012768 AAH12768 BC014920 AAH14920 BC073768 AAH73768 BP231480 BT019888 AAV38691 CR407614 CAG28542 CR536489 CAG38728 DQ891304 ABM82230 DQ893349 ABM84275 DQ894489 ABM85415 DQ896669 ABM87668 FJ224323 ACI46015 S74571 AAB20722 U90906 AAB51056 X16477 CAA34498 X54079 CAA38016 NM_001540 NP_001531
Function	Involved in stress resistance and actin organization.
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Tissue Specificity	Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle. {ECO:0000269|PubMed:1560006}.
Top Pathways	VEGF signaling pathway, MAPK signaling pathway, Amoebiasis, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HSPB1-Over-expression-Lysate - LY12043a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

HSPB1 293 Cell Lysate - 400582 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

HSP27 Overexpression Lysate (Native) - NBL1-11757 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

HSP 27 (h): 293 Lysate - sc-113042 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

HSP 27 (h): 293T Lysate - sc-174710 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

HSP 27 (h2): 293T Lysate - sc-174711 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

HSP 27 (h4): 293T Lysate - sc-174723 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

HSPB1 Over-expression Lysate Product - GWB-805A66 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

HSP27 Overexpression Lysate (Denatured) - H00003315-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

HSPB1-knockout Cell lysate - LC810109 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human HSPB1 Knockdown Stable Cell Line - CSC-DC007318 from Creative biogene Category Cell Line Species Human

Human HSPB1 Knockout Cell Line-HeLa - CSC-RT0530 from Creative biogene Category Cell Line Species Human

HSPB1 KO Cell Lysate-HeLa - CLKO-0035 from Creative biogene Category Cell Lysate

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