Gene Symbol | MC3R |
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Entrez Gene | 4159 |
Alt Symbol | BMIQ9, MC3, MC3-R, OB20, OQTL |
Species | Human |
Gene Type | protein-coding |
Description | melanocortin 3 receptor |
Other Description | melanocortin receptor 3|obesity quantitative trait locus |
Swissprots | Q4KN27 Q9H517 P41968 |
Accessions | AAC13541 CAJ56570 EAW75566 P41968 AY227893 AAO72726 BC069105 AAH69105 BC069591 BC069599 AAH69599 BC096702 AAH96702 BC096737 AAH96737 BC098169 AAH98169 BC098351 AAH98351 HQ447472 ADQ31958 NM_019888 NP_063941 |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. {ECO:0000250|UniProtKB:P33033}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Brain, placental, and gut tissues. |
Top Pathways | Neuroactive ligand-receptor interaction |
MC3-R (C-20) - sc-6878 from Santa Cruz Biotechnology
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MC3-R (H-88) - sc-8990 from Santa Cruz Biotechnology
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Anti-MC3 Receptor antibody - ab21228 from Abcam
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Anti-MC3 Receptor antibody - ab21231 from Abcam
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Anti-MC3 Receptor antibody - ab93368 from Abcam
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Anti-MC3 Receptor antibody - ab31309 from Abcam
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Anti-MC3 Receptor antibody - C-terminal - ab140864 from Abcam
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Anti-MC3R / MC3 Receptor Antibody (1st Extracellular Domain) - LS-C8978 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (3rd Cytoplasmic Domain) - LS-C8975 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (Internal, APC) - LS-C279432 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (Internal, AP) - LS-C279430 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (Internal, Biotin) - LS-C279433 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (Internal, PE) - LS-C279435 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (Internal, Azide-free, HRP) - LS-C279436 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (Internal, FITC) - LS-C279434 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (aa1-80) - LS-C311576 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody - LS-C341763 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (Internal) - LS-C330534 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (N-Terminus) - LS-C55103 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody - LS-C332325 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (aa86-112) IHC-plus⢠- LS-B10506 from LifeSpan Bioscience
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Anti-MC3R / MC3 Receptor Antibody (C-Terminus) IHC-plus⢠- LS-A452 from LifeSpan Bioscience
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Melanocortin-3 R/MC3R Antibody - NB100-1501 from Novus Biologicals
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Melanocortin-3 R/MC3R Antibody - H00004159-A01 from Novus Biologicals
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MC3 Receptor Polyclonal Antibody - bs-7558R from Bioss
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