| Gene Symbol |
MC3R
|
| Entrez Gene |
4159
|
| Alt Symbol |
BMIQ9, MC3, MC3-R, OB20, OQTL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
melanocortin 3 receptor
|
| Other Description |
melanocortin receptor 3|obesity quantitative trait locus
|
| Swissprots |
Q4KN27 Q9H517 P41968
|
| Accessions |
AAC13541 CAJ56570 EAW75566 P41968 AY227893 AAO72726 BC069105 AAH69105 BC069591 BC069599 AAH69599 BC096702 AAH96702 BC096737 AAH96737 BC098169 AAH98169 BC098351 AAH98351 HQ447472 ADQ31958 NM_019888 NP_063941
|
| Function |
Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. {ECO:0000250|UniProtKB:P33033}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Brain, placental, and gut tissues.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|