Gene Symbol | MC3R |
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Entrez Gene | 4159 |
Alt Symbol | BMIQ9, MC3, MC3-R, OB20, OQTL |
Species | Human |
Gene Type | protein-coding |
Description | melanocortin 3 receptor |
Other Description | melanocortin receptor 3|obesity quantitative trait locus |
Swissprots | Q4KN27 Q9H517 P41968 |
Accessions | AAC13541 CAJ56570 EAW75566 P41968 AY227893 AAO72726 BC069105 AAH69105 BC069591 BC069599 AAH69599 BC096702 AAH96702 BC096737 AAH96737 BC098169 AAH98169 BC098351 AAH98351 HQ447472 ADQ31958 NM_019888 NP_063941 |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. {ECO:0000250|UniProtKB:P33033}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Brain, placental, and gut tissues. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human MC3 Receptor full length protein - ab132226 from Abcam
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Human MC3 Receptor protein fragment - ab158864 from Abcam
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MC3 Receptor peptide - ab108366 from Abcam
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MC3 Receptor peptide (2-13) (Aminoterminal end) - ab45722 from Abcam
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MC3R / MC3 Receptor Antibody Blocking Peptide - LS-E28973 from LifeSpan Bioscience
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MC3R / MC3 Receptor Blocking Peptide - LS-E25862 from LifeSpan Bioscience
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MC3R / MC3 Receptor Antibody Blocking Peptide - LS-E9742 from LifeSpan Bioscience
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Recombinant Human Melanocortin-3 R/MC3R Protein - H00004159-Q01 from Novus Biologicals
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Recombinant Human Melanocortin-3 R/MC3R Protein - H00004159-P01 from Novus Biologicals
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MC3R-Antibody-Center-Blocking-Peptide - BP8719c from Abgent, a WuXi AppTec company
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MC3 Receptor blocking peptide - GTX89585-PEP from GeneTex
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MC3 Receptor Peptide - AC21-0692-P from Abcore
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MC3-R - H00004159-G01 from Acris Antibodies
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MC3-R - H00004159-P01-10 from Acris Antibodies
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MC3-R - H00004159-P01-25 from Acris Antibodies
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MC3-R - H00004159-Q01-10 from Acris Antibodies
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MC3-R - H00004159-Q01-25 from Acris Antibodies
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MC3-R control peptide - AP10124CP-N from Acris Antibodies
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MC3-R Control Peptide - AP10125CP-N from Acris Antibodies
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MC3-R control peptide - AP10126CP-N from Acris Antibodies
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Melanocortin 3 Receptor Peptide - 45-881P from ProSci
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MC3R fusion protein - Ag15411 from Proteintech Group
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MC3R fusion protein - Ag15292 from Proteintech Group
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Recombinant Human MC3R, GST-tagged - MC3R-772H from Creative Biomart
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MC3-R (1-88) - sc-4280 WB from Santa Cruz Biotechnology
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