RANBP3

Gene Symbol	RANBP3
Entrez Gene	8498
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	RAN binding protein 3
Other Description	RAN-binding protein-3|ran-binding protein 3
Swissprots	Q9UG74 Q9BT47 O75759 O60405 Q9H6Z4 B2RAT8 O75760
Accessions	AAC14485 EAW69120 EAW69121 EAW69122 EAW69123 EAW69124 Q9H6Z4 AK025300 BAB15106 AK125183 AK222813 AK222990 BAD96710 AK299260 BAH12980 AK299856 BAH13150 AK301942 BAH13589 AK308205 AK314343 BAG36985 AL050149 CAB43293 BC004349 AAH04349 BM786367 CB306615 DQ234346 ABB29975 Y08697 CAA69956 Y08698 CAA69957 Y08699 CAA69958 XM_006722928 XP_006722991 XM_006722929 XP_006722992 XM_011528391 XP_011526693 XM_011528392 XP_011526694 XM_011528393 XP_011526695 XM_011528394 XP_011526696 NM_003624 NP_003615 NM_007320 NP_015559 NM_007322 NP_015561 NM_007321 NM_001300865 NP_001287794
Function	Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF- beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. {ECO:0000269|PubMed:11425870, ECO:0000269|PubMed:11571268, ECO:0000269|PubMed:11932251, ECO:0000269|PubMed:19289081, ECO:0000269|PubMed:9637251}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19289081}. Nucleus {ECO:0000269|PubMed:19289081}.
Tissue Specificity	Widely expressed with high levels in testis and heart. {ECO:0000269|PubMed:9637251}.
Top Pathways	HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Phospho-RanBP3 (Ser58) Antibody - 9380 from Cell Signaling Technology Prices $287.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

Ran BP-3 (C-5) - sc-373678 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Ran BP-3 (D-2) - sc-377253 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Ran BP-3 (C-14) - sc-47351 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Ran BP-3 (52) - sc-136055 from Santa Cruz Biotechnology Prices $279.00 Sizes 50 µg/0.5 ml Host Mouse Clonality Monoclonal

Anti-RanBP3 antibody - ab2939 from Abcam Prices $370.00 Sizes 200 µg Host Rabbit Clonality Polyclonal

Anti-RanBP3 antibody - ab84672 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RanBP3 antibody - ab155327 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RanBP3 antibody - ab129484 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RanBP3 antibody - ab56341 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-RanBP3 antibody [AT12E11] - ab194212 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone AT12E11

Anti-RanBP3 antibody [EPR5088(2)] - ab134052 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR5088(2)

Anti-RANBP3 Antibody (aa1-13) - LS-C38725 from LifeSpan Bioscience Prices $530.00 Sizes 200 µg Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (Ser58) - LS-C191246 from LifeSpan Bioscience Prices $445.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (aa26-55, AP) - LS-C267806 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (aa26-55, APC) - LS-C267807 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (aa26-55, FITC) - LS-C267809 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (aa26-55, Biotin) - LS-C267808 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (aa26-55, Azide-free, HRP) - LS-C267810 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (aa26-55, PE) - LS-C267811 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (aa25-55) - LS-C324520 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (N-Terminus) - LS-C112210 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (aa150-200) - LS-C288314 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RANBP3 Antibody (Internal, clone EPR5088(2)) - LS-C152433 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR5088(2)

Anti-RANBP3 Antibody (aa26-55) - LS-C162431 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Search more