CSRP3

Gene Symbol CSRP3
Entrez Gene 8048
Alt Symbol CLP, CMD1M, CMH12, CRP3, LMO4, MLP
Species Human
Gene Type protein-coding
Description cysteine and glycine-rich protein 3 (cardiac LIM protein)
Other Description LIM domain only 4|cardiac LIM domain protein|cysteine and glycine-rich protein 3|muscle lim protein isoform
Swissprots Q9P131 P50461
Accessions AAD00189 ABN05285 CAC60376 EAW68355 EAW68356 P50461 AA192614 AF121260 AAF28868 AI184002 AJ711422 AK313289 BAG36097 BC005900 AAH05900 BC024010 AAH24010 BC057221 AAH57221 BF671742 DQ893125 ABM84051 DQ896402 ABM87401 JN898958 AFH66949 U20324 AAA91104 U49837 AAA92571 U72899 AAD00183 NM_003476 NP_003467
Function Positive regulator of myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. It is essential for calcineurin anchorage to the Z line. Required for stress-induced calcineurin-NFAT activation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:18505755}. Cytoplasm, cytoskeleton {ECO:0000305}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Mainly cytoplasmic (By similarity). In the nucleus it associates with the actin cytoskeleton (Potential). In the Z line, found associated with GLRX3 (By similarity). {ECO:0000250, ECO:0000305}.
Tissue Specificity Cardiac and slow-twitch skeletal muscles.

CSRP3-Over-expression-Lysate - LY13068a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CSRP3 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CSRP3 gene

CSRP3 293 Cell Lysate - 408710 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CSRP3 Overexpression Lysate (Native) - NBL1-09543 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CSRP3 Overexpression Lysate (Adult Normal) [NBL1-09543] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CSRP3.

CSRP3 Over-expression Lysate Product - GWB-B216F1 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

CSRP3 Overexpression Lysate (Native) - NBP2-09457 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CSRP3 Overexpression Lysate (Adult Normal) [NBP2-09457] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CSRP3.

Panoply™ Human CSRP3 Knockdown Stable Cell Line - CSC-DC003736 from Creative biogene

Category Cell Line
Species Human
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