FBXL7

Gene Symbol FBXL7
Entrez Gene 23194
Alt Symbol FBL6, FBL7
Species Human
Gene Type protein-coding
Description F-box and leucine-rich repeat protein 7
Other Description F-box protein Fbl7|F-box/LRR-repeat protein 7
Swissprots O94926 B9EGF1 D6RDY7 Q9UJT9
Accessions CAJ42767 EAX08028 EAX08029 Q9UJT9 AB020647 BAA74863 AF174593 AAF04514 AF199356 AAF09248 AK021671 AK309585 AY425960 AAR07953 BC050571 BC075061 AAH75061 BC136424 AAI36425 BU633031 XM_005248273 XP_005248330 XM_011513998 XP_011512300 NM_001278317 NP_001265246 NM_012304 NP_036436
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest. {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Localizes to the centrosome during spindle formation. {ECO:0000250}.

FBXL7-Over-expression-Lysate - LY10603a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag FBXL7 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FBXL7 gene (Lane 2, Cat. #LY10603a).

FBXL7 overexpression lysate - LY415865 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

FBXL7 Overexpression Lysate (Native) - NBP2-07467 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

Panoply™ Human FBXL7 Knockdown Stable Cell Line - CSC-DC005582 from Creative biogene

Category Cell Line
Species Human
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