BPHL

Gene Symbol BPHL
Entrez Gene 670
Alt Symbol BPH-RP, MCNAA, VACVASE
Species Human
Gene Type protein-coding
Description biphenyl hydrolase-like (serine hydrolase)
Other Description biphenyl hydrolase-related protein|breast epithelial mucin-associated antigen|valacyclovir hydrolase|valacyclovirase
Swissprots Q3KP51 Q13855 Q86WA6 Q00306
Accessions EAW55119 EAW55120 EAW55121 EAW55122 EAW55123 Q86WA6 AJ617684 CAE85120 AK297518 BAG59925 AK314909 BAG37421 AL832502 BC037778 AAH37778 BC106901 AAI06902 BM977067 DC352501 X57653 CAA40859 X81372 CAA57137 NM_001302777 NP_001289706 NM_004332 NP_004323 NR_026648 NR_026649
Function Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. {ECO:0000269|PubMed:18256025}.
Tissue Specificity Expressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle. {ECO:0000269|PubMed:7759552}.

VACVase (E-3) - sc-514189 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VACVase (E-3): sc-514189. Western blot analysis of VACVase expression in non-transfected: sc-117752 (A), mouse VACVase transfected: sc-124534 (B), Hep G2 (C) and Caki-1 (D) 293T whole cell lysates and human liver tissue extract (E).

VACVase (H-73) - sc-366824 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VACVase (H-73): sc-366824. Western blot analysis of VACVase expression in non-transfected: sc-117752 (A) and mouse VACVase transfected: sc-124534 (B) 293T whole cell lysates and mouse liver (C) and mouse kidney (D) tissue extracts.

VACVase (P-19) - sc-54454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VACVase (P-19): sc-54454. Western blot analysis of VACVase expression in non-transfected: sc-117752 (A) and mouse VACVase transfected: sc-124534 (B) 293T whole cell lysates.

Anti-BPHL antibody - ab72851 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-BPHL antibody (ab72851) at 1/500 dilution + human liver lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-BPHL antibody - ab173910 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-BPHL antibody (ab173910) at 1/100 dilution + 293 cell line lysate at 35 µgSecondaryanti-Rabbit HRP conjugated antibody at 1/10000 dilutiondeveloped using the ECL technique

Anti-BPHL antibody - ab123003 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BPHL antibody (ab123003) at 1 µg/ml + THP1 cell lysate at 10 µg

Anti-MCNAA / BPHL Antibody (aa96-124, PE) - LS-C252655 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCNAA / BPHL Antibody (aa96-124, AP) - LS-C252978 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCNAA / BPHL Antibody (aa96-124, APC) - LS-C252979 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCNAA / BPHL Antibody (aa96-124, Biotin) - LS-C252980 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCNAA / BPHL Antibody (aa96-124, FITC) - LS-C252981 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCNAA / BPHL Antibody (aa96-124, Azide-free, HRP) - LS-C252982 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCNAA / BPHL Antibody (aa34-83) - LS-C145937 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BPHL antibody LS-C145937 Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.

Anti-MCNAA / BPHL Antibody (aa95-124) - LS-C319864 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCNAA / BPHL Antibody - LS-C306560 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MCNAA / BPHL Antibody (aa96-124) - LS-C159180 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BPHL Antibody western blot of 293 cell line lysates (35 ug/lane). The BPHL antibody detected the BPHL protein (arrow).

ATPB Antibody (4E5) - NBP2-02249 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E5
Western Blot: ATPB Antibody (4E5) [NBP2-02249] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATPB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATPB.

BPHL Antibody - NBP2-38328 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BPHL Antibody [NBP2-38328] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4

BPHL Antibody - NBP1-88373 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BPHL Antibody [NBP1-88373] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4

BPHL Antibody - H00000670-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: BPHL Antibody [H00000670-B01] - BPHL MaxPab polyclonal antibody (B01), Lot # 08077 WULz. Western Blot analysis of BPHL expression in human liver.

Anti-BPHL antibody produced in mouse - SAB1400026 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-BPHL, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400026</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~32.5 kDa using human liver lysate.

BPHL antibody - N-terminal region (ARP61857_P050) - ARP61857_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BPHL-Antibody-Center - AP18229c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
BPHL Antibody (Center) (Cat. #AP18229c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the BPHL antibody detected the BPHL protein (arrow).

BPHL antibody [N1C3] - GTX105864 from GeneTex

Host Rabbit
Clonality Polyclonal

BPHL Antibody - middle region (OAAB13742) - OAAB13742 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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