POLR2M

Gene Symbol POLR2M
Entrez Gene 81488
Alt Symbol GCOM1, GRINL1A, Gdown, Gdown1
Species Human
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide M
Other Description DNA-directed RNA polymerase II subunit M, isoforms 4/5|GRINL1A downstream protein Gdown4|glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A|protein GRINL1A|protein GRINL1A, isoforms 4/5
Swissprots Q6K051 Q6EF02 Q6EF46 Q8NC58 Q6EEV7 Q6EF00 Q6EFN8 Q9Y3V6 Q96NF5 Q6ZQZ3 Q6K046 Q6K050 Q6EER8 Q8NCF3 D2E9U7 Q96DI5 P0CAP1 Q6EM48 Q96JB7 Q6EEV4 P0CAP2 Q6EF01 Q6EEV3 Q6EES2
Accessions CAF86856 EAW77525 EAW77527 P0CAP2 Q6EEV4 AF086209 AF326773 AAK92284 AK074767 BAC11193 AK074955 BAC11313 AK128618 BAC87533 AK223571 BAD97291 AK308873 AL050091 CAB43263 AM392721 CAL37599 AY339380 AAQ82540 AY341344 AAQ76830 AY353061 AAQ76837 BC001510 AAH01510 BF939412 BI833260 BQ072611 DQ893035 ABM83961 DQ896276 ABM87275 NM_001018102 NP_001018112 NM_015532 NP_056347 NR_027390
Function Plays a role in cellular signaling via Rho-related GTP- binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Cell junction {ECO:0000269|PubMed:18849881, ECO:0000269|PubMed:21240187}. Note=Detected predominantly at the intercalated disk in cardiomyocytes, and at low levels on sarcomeric Z disks. Colocalizes with F-actin. Colocalizes with cortical actin (By similarity). {ECO:0000250}.
Tissue Specificity Detected in heart, liver, skeletal muscle, placenta, small intestine, lung, prostate and testis. {ECO:0000269|PubMed:15233991, ECO:0000269|PubMed:20093627}.

GRINL1A (G-13) - sc-168038 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GRINL1A/B (E-16) - sc-168037 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GRINL1A/B (E-16): sc-168037. Western blot analysis of GRINL1A expression in non-transfected: sc-117752 (A) and human GRINL1A transfected: sc-128737 (B) 293T whole cell lysates.

GRINL1A/B (I-19) - sc-168039 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GRINL1A/B (I-19): sc-168039. Western blot analysis of GRINL1A expression in non-transfected 293T: sc-117752 (A), mouse GRINL1A transfected 293T: sc-120635 (B), HeLa (C) and NIH/3T3 (D) whole cell lysates.

Anti-GRINL1A antibody - ab113427 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of GRINL1A in Human lung tissue with ab113427 at 20 ug/mL.

Anti-GRINL1A antibody - ab69202 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-GRINL1A antibody (ab69202) at 1/500 dilutionLane 1 : GRINL1A transfected 293T lysateLane 2 : Non transfected 293T lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-POLR2M Antibody (aa269-369) - LS-C308117 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-POLR2M Antibody (C-Terminus) - LS-C145739 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GRINL1A antibody LS-C145739 Western blot of Placenta lysate. Antibody concentration 1 ug/ml.

Anti-POLR2M Antibody (aa283-332) - LS-C145740 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GRINL1A antibody LS-C145740 Western blot of Fetal Lung lysate. Antibody concentration 1 ug/ml.

GCOM1 Antibody - NBP2-16627 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GCOM1 Antibody [NBP2-16627] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE gel, diluted at 1:1000.

GRINL1A Antibody - H00081488-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: GRINL1A Antibody [H00081488-B01] - analysis of GRINL1A expression in transfected 293T cell line by GRINL1A MaxPab polyclonal antibody (B01). Lane 1: GRINL1A transfected lysate (41.70 KDa). Lane 2: Non-transfected lysate.

GRINL1A Antibody (2E4) - H00081488-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E4

Anti-GRINL1A (206-220) antibody produced in rabbit - SAB1104562 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-GRINL1A, (C-terminal) antibody produced in mouse - SAB1403384 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E4
<B>Immunoblotting</B><BR/>Monoclonal Anti-GRINL1A: <B>Cat. No. SAB1403384</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.1 kDa using immunogen protein lysate.

Anti-GRINL1A (146-160) antibody produced in rabbit - SAB1104561 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human GRINL1A was separated on SDS-PAGE, blotted with Anti-GRINL1A (146-160) (<B>Cat. No. SAB1104561</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-GRINL1A antibody produced in rabbit - SAB2107692 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GRINL1A: <B>Cat. No. SAB2107692</B>: Western blot analysis of GRINL1A in Fetal Lung with GRINL1A (glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A) antibody against the C terminal of GRINL1A (50 μg) antibody at 1.0 μg/mL.

Anti-GRINL1A antibody produced in rabbit - SAB2107691 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GRINL1A: <B>Cat. No. SAB2107691</B>: Western blot analysis of GRINL1A in Placenta with GRINL1A (glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A) antibody against the C terminal of GRINL1A (50 μg) antibody at 1.0 μg/mL.

GRINL1A antibody - C-terminal region (ARP62221_P050) - ARP62221_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GRINL1A antibody - C-terminal region (ARP62222_P050) - ARP62222_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GRINL1A antibody - H00081488-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of GRINL1A expression in transfected 293T cell line (H00081488-T01) by GRINL1A MaxPab polyclonal antibody.Lane 1: GRINL

GRINL1A antibody - H00081488-M04 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E4

GRINL1A Antibody - GWB-MW522I from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit

GRINL1A Antibody - GWB-MW521H from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit

Anti-POLR2M monoclonal antibody - DCABH-200655 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

Anti-glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A - 08A081488 from MP Biomedicals

Prices $456.30
Sizes 100 μg
Host Mouse
Clonality Monoclonal
Clone 2E4

POLR2M antibody - pab0963-P from Covalab

Host Rabbit
Clonality Polyclonal
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