POLR2M

Gene Symbol POLR2M
Entrez Gene 81488
Alt Symbol GCOM1, GRINL1A, Gdown, Gdown1
Species Human
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide M
Other Description DNA-directed RNA polymerase II subunit M, isoforms 4/5|GRINL1A downstream protein Gdown4|glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A|protein GRINL1A|protein GRINL1A, isoforms 4/5
Swissprots Q6K051 Q6EF02 Q6EF46 Q8NC58 Q6EEV7 Q6EF00 Q6EFN8 Q9Y3V6 Q96NF5 Q6ZQZ3 Q6K046 Q6K050 Q6EER8 Q8NCF3 D2E9U7 Q96DI5 P0CAP1 Q6EM48 Q96JB7 Q6EEV4 P0CAP2 Q6EF01 Q6EEV3 Q6EES2
Accessions CAF86856 EAW77525 EAW77527 P0CAP2 Q6EEV4 AF086209 AF326773 AAK92284 AK074767 BAC11193 AK074955 BAC11313 AK128618 BAC87533 AK223571 BAD97291 AK308873 AL050091 CAB43263 AM392721 CAL37599 AY339380 AAQ82540 AY341344 AAQ76830 AY353061 AAQ76837 BC001510 AAH01510 BF939412 BI833260 BQ072611 DQ893035 ABM83961 DQ896276 ABM87275 NM_001018102 NP_001018112 NM_015532 NP_056347 NR_027390
Function Plays a role in cellular signaling via Rho-related GTP- binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Cell junction {ECO:0000269|PubMed:18849881, ECO:0000269|PubMed:21240187}. Note=Detected predominantly at the intercalated disk in cardiomyocytes, and at low levels on sarcomeric Z disks. Colocalizes with F-actin. Colocalizes with cortical actin (By similarity). {ECO:0000250}.
Tissue Specificity Detected in heart, liver, skeletal muscle, placenta, small intestine, lung, prostate and testis. {ECO:0000269|PubMed:15233991, ECO:0000269|PubMed:20093627}.

Human GRINL1A full length protein - ab132788 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132788 stained with Coomassie Blue.

POLR2M Antibody Blocking Peptide - LS-E22732 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

POLR2M Antibody Blocking Peptide - LS-E22731 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human GRINL1A Protein - H00081488-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human GRINL1A Protein - H00081488-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

GRINL1A - H00081488-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

GRINL1A - H00081488-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

GRINL1A - H00081488-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

GRINL1A - H00081488-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

Recombinant Human POLR2M, His-tagged - POLR2M-28539TH from Creative Biomart

Category Protein
Source E. coli

Recombinant Human DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5(POLR2M) - CSB-YP715729HU CSB-EP715729HU CSB-BP715729HU CSB-MP715729HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human DNA-directed RNA polymerase II subunit GRINL1A(POLR2M) - CSB-YP316685HU CSB-EP316685HU CSB-BP316685HU CSB-MP316685HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

POLR2M Peptide, Human - M34GP12103H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

GRINL1A Recombinant Protein Antigen - NBP2-57432PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

DNA-directed RNA polymerase II subunit GRINL1A (POLR2M), Recombinant Protein - MBS1250835 from MyBioSource

Category Protein
Prices $1,135.00, $1,135.00, $1,365.00, $1,365.00, $1,805.00, $1,805.00, $2,270.00, $2,270.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 (POLR2M), Recombinant Protein - MBS1338920 from MyBioSource

Category Protein
Prices $890.00, $890.00, $1,115.00, $1,115.00, $1,305.00, $1,305.00, $1,760.00, $1,760.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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