| Gene Symbol |
SLC17A7
|
| Entrez Gene |
57030
|
| Alt Symbol |
BNPI, VGLUT1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 17 (vesicular glutamate transporter), member 7
|
| Other Description |
brain-specific Na(+)-dependent inorganic phosphate cotransporter|brain-specific Na-dependent inorganic phosphate cotransporter|solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7|solute carrier family 17 member 7|vesicular glutamate transporter 1
|
| Swissprots |
Q6PCD0 Q9P2U7 B4DG46 B4DFR9
|
| Accessions |
EAW52485 Q9P2U7 AB032436 BAA92875 AK057879 AK091061 AK095659 AK289622 BAF82311 AK294226 BAG57530 AK294405 BAG57657 BC059379 AAH59379 BG701511 BQ636968 BU732143 NM_020309 NP_064705
|
| Function |
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. {ECO:0000269|PubMed:10820226}.
|
| Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell junction, synapse, synaptosome {ECO:0000250}.
|
| Tissue Specificity |
Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe. {ECO:0000269|PubMed:10820226}.
|
| Top Pathways |
Synaptic vesicle cycle, Glutamatergic synapse, Nicotine addiction, Retrograde endocannabinoid signaling
|