Gene Symbol | CGN |
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Entrez Gene | 57530 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cingulin |
Other Description | - |
Swissprots | Q9P2M7 Q5T386 Q9NR25 A7MD22 A6H8L3 |
Accessions | EAW53434 EAW53435 Q9P2M7 AB037740 BAA92557 AF263462 AAF74498 AK290007 BAF82696 BC146657 AAI46658 BC150604 AAI50605 BC152445 AAI52446 BP331021 BX647343 CN359389 DQ656045 DQ656046 XM_005245365 XP_005245422 XR_921902 NM_020770 NP_065821 |
Function | Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. |
Subcellular Location | Cell junction, tight junction {ECO:0000250}. Note=Localizes to the apical junction complex composed of tight and adherens junctions. {ECO:0000250}. |
Tissue Specificity | Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart. |
Top Pathways | Tight junction |
Cingulin (H-180) - sc-66831 from Santa Cruz Biotechnology
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Cingulin (G-6) - sc-365264 from Santa Cruz Biotechnology
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Cingulin (C-17) - sc-46572 from Santa Cruz Biotechnology
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Cingulin (N-12) - sc-46574 from Santa Cruz Biotechnology
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Cingulin (N-16) - sc-46575 from Santa Cruz Biotechnology
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Anti-Cingulin antibody - ab117778 from Abcam
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Anti-Cingulin antibody - ab117796 from Abcam
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Anti-CGN / Cingulin Antibody (aa4-24, clone 139.3.4) - LS-C84909 from LifeSpan Bioscience
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Anti-CGN / Cingulin Antibody - LS-C193729 from LifeSpan Bioscience
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Anti-CGN / Cingulin Antibody (aa350-400) - LS-C286235 from LifeSpan Bioscience
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Anti-CGN / Cingulin Antibody (aa200-250) - LS-C290014 from LifeSpan Bioscience
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Anti-CGN / Cingulin Antibody (N-Terminus) - LS-C345979 from LifeSpan Bioscience
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Cingulin Antibody - NBP1-89600 from Novus Biologicals
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Cingulin Antibody - NBP1-89602 from Novus Biologicals
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Cingulin Antibody - NBP1-89601 from Novus Biologicals
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Cingulin Antibody - NBP2-15904 from Novus Biologicals
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Anti-CGN antibody produced in rabbit - HPA027586 from Sigma-Aldrich
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Anti-CGN antibody produced in rabbit - HPA027587 from Sigma-Aldrich
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Anti-CGN antibody produced in rabbit - HPA027657 from Sigma-Aldrich
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CGN Antibody - N-terminal region (ARP42911_P050) - ARP42911_P050 from Aviva Systems Biology
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CGN antibody - GTX120159 from GeneTex
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Cingulin antibody - 10R-C193a from Fitzgerald
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CGN antibody - 70R-16373 from Fitzgerald
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Cingulin antibody - 21369-1-AP from Acris Antibodies
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Cingulin antibody - BM5098 from Acris Antibodies
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