Gene Symbol |
CGN
|
Entrez Gene |
57530
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cingulin
|
Other Description |
-
|
Swissprots |
Q9P2M7 Q5T386 Q9NR25 A7MD22 A6H8L3
|
Accessions |
EAW53434 EAW53435 Q9P2M7 AB037740 BAA92557 AF263462 AAF74498 AK290007 BAF82696 BC146657 AAI46658 BC150604 AAI50605 BC152445 AAI52446 BP331021 BX647343 CN359389 DQ656045 DQ656046 XM_005245365 XP_005245422 XR_921902 NM_020770 NP_065821
|
Function |
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
|
Subcellular Location |
Cell junction, tight junction {ECO:0000250}. Note=Localizes to the apical junction complex composed of tight and adherens junctions. {ECO:0000250}.
|
Tissue Specificity |
Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart.
|
Top Pathways |
Tight junction
|