DDX42

Gene Symbol	DDX42
Entrez Gene	11325
Alt Symbol	DDX42P, RHELP, RNAHP, SF3B8, SF3b125
Species	Human
Gene Type	protein-coding
Description	DEAD (Asp-Glu-Ala-Asp) box helicase 42
Other Description	ATP-dependent RNA helicase DDX42|DEAD (Asp-Glu-Ala-Asp) box polypeptide 42|SF3b DEAD box protein|splicing factor 3B-associated 125 kDa protein|splicing factor 3b, subunit 8
Swissprots	Q96HR7 Q9Y3V8 Q68G51 O75619 A8KA43 Q86XP3 Q96BK1 A6NML1
Accessions	EAW94276 EAW94277 EAW94278 Q86XP3 AB036090 BAC66466 AF083255 AAC32396 AF147429 AK001964 BAG50996 AK095772 BAG53126 AK096751 AK122737 BAG53696 AK126480 BAG54335 AK292908 BAF85597 AL050096 CAB43268 AL527653 AL545851 BC008208 AAH08208 BC015505 AAH15505 BC078667 AAH78667 BC093081 AAH93081 BK000566 DAA00077 DA440475 XM_006721657 XP_006721720 XM_011524259 XP_011522561 NM_007372 NP_031398 NM_203499 NP_987095
Function	ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm. {ECO:0000269|PubMed:16397294, ECO:0000269|PubMed:19377511}.
Subcellular Location	Cytoplasm. Nucleus speckle. Nucleus, Cajal body. Note=Isoform 2 is present in Cajal bodies (CBs) and nuclear speckles.
Tissue Specificity	Expressed in several cell lines (at protein level). Expressed in liver, lung, tonsil, thymus, muscle and pancreatic islets. {ECO:0000269|PubMed:10727850, ECO:0000269|PubMed:16397294}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DDX42 ELISA Kit (Sandwich ELISA) - LS-F11286 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 78-5000 pg/ml

ATP-dependent RNA helicase DDX42 (DDX42), Human, ELISA Kit - E01A1834 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

ATP-dependent RNA helicase DDX42, DDX42, Human, ELISA Kit - E14799h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 78-5000 pg/mL

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7206404 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7223054 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7244074 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7228239 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7233667 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7247499 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7202976 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7214503 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7209907 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7231923 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7231941 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP dependent RNA helicase DDX42 (DDX42), ELISA Kit - MBS7235721 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Mouse DDX42 ELISA Kit (Custom ELISA) - LS-F17426 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Chicken DDX42 ELISA Kit (Custom ELISA) - LS-F17425 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Human ATP-dependent RNA helicase DDX42 ELISA Kit - abx250947 from Abbexa Category ELISA Kit Range 78 pg/ml - 5000 pg/ml

Human ATP-dependent RNA helicase DDX42 ELISA Kit - EKE54646 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 34 pg/ml Range 78-5000 pg/mL

DDX42 - EKH3304 from Nordic BioSite Sensitivity 46.9pg/ml Range 78-5000pg/ml

DDX42 ELISA Kit (Human) (OKEH02374) - OKEH02374 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 34 pg/mL Range 78 - 5,000 pg/mL

Human DDX42 ELISA Kit - E004034 from Biobool Category ELISA Kit Sensitivity 0.1 ng/mL.

Human ATP-dependent RNA helicase DDX42 ELISA Kit - EK3467 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Sensitivity less than 34pg/ml Range 78-5000 pg/mL

ATP-dependent RNA helicase DDX42, ELISA Kit - MBS9427301 from MyBioSource Category ELISA Kit Prices $670.00 Sizes 96 tests Sensitivity Less than 34pg/mL Range 78-5000 pg/mL

ATP-dependent RNA helicase DDX42, ELISA Kit - MBS2883745 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 78-5000 pg/mL

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