PTPRH

Gene Symbol	PTPRH
Entrez Gene	5794
Alt Symbol	R-PTP-H, SAP1
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, receptor type, H
Other Description	receptor-type tyrosine-protein phosphatase H|stomach cancer-associated protein tyrosine phosphatase 1|transmembrane-type protein-tyrosine phosphatase type H
Swissprots	Q9HD43 C9JCH2 Q15426 Q2NKN9 Q2NKP0
Accessions	AAF91411 EAW72348 Q9HD43 AA573849 AK097257 BC111715 AAI11716 BC111716 AAI11717 D15049 BAA03645 XM_011527183 XP_011525485 XM_011527184 XP_011525486 XM_011527185 XP_011525487 XM_011527186 XP_011525488 XM_011527187 XP_011525489 XM_011527188 XP_011525490 XM_011527189 XP_011525491 XM_011527190 XP_011525492 XR_935847 NM_001161440 NP_001154912 NM_002842 NP_002833
Function	May contribute to contact inhibition of cell growth and motility by mediating the dephosphorylation of focal adhesion- associated substrates and thus negatively regulating integrin- promoted signaling processes. Induces apoptotic cell death by at least two distinct mechanisms: inhibition of cell survival signaling mediated by PI 3-kinase, Akt, and ILK and activation of a caspase-dependent proapoptotic pathway. Inhibits the basal activity of LCK and its activation in response to TCR stimulation and TCR-induced activation of MAP kinase and surface expression of CD69. Inhibits TCR-induced tyrosine phosphorylation of LAT and ZAP70. Inhibits both basal activity of DOK1 and its CD2-induced tyrosine phosphorylation. Induces dephosphorylation of p130cas, focal adhesion kinase and c-Src. Reduces migratory activity of Jurkat cells. {ECO:0000269|PubMed:11278335, ECO:0000269|PubMed:12101188, ECO:0000269|PubMed:12837766, ECO:0000269|PubMed:15850787}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:12879010}.
Tissue Specificity	Expressed at high levels in the brain, spleen and liver and at lower levels in the heart and stomach. Expressed in pancreatic and colorectal cancer cells, but not in normal pancreas or colon. Expression in hepatocellular carcinoma is related to the differentiation status of the tumor and expression is inversely related to tumor aggressiveness. {ECO:0000269|PubMed:12837766, ECO:0000269|PubMed:12879010, ECO:0000269|PubMed:8294459}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PTPRH ELISA Kit - HP0173 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine PTPRH ELISA Kit - AP0173 from NeoScientific Category ELISA Kit Prices $300.00, $480.00 Sizes 100 µl, 200 µl

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS038413 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS754452 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS022041 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS064553 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS021803 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS754997 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS048186 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS731199 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS728135 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS061001 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS019279 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS749141 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS746585 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS006755 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS722788 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS733541 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H - MBS034924 from MyBioSource Category ELISA Kit Prices $435.00, $600.00 Sizes 48 strip wells, 96 strip wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS067952 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS006259 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS006022 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS015509 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS037793 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Tyrosine Phosphatase Receptor Type H, ELISA Kit - MBS015267 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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