FIP1L1

Gene Symbol FIP1L1
Entrez Gene 81608
Alt Symbol FIP1, Rhe, hFip1
Species Human
Gene Type protein-coding
Description factor interacting with PAPOLA and CPSF1
Other Description FIP1 like 1|FIP1-like 1 protein|FIP1L1 cleavage and polyadenylation specific factor subunit|factor interacting with PAP|pre-mRNA 3'-end-processing factor FIP1|rearranged in hypereosinophilia
Swissprots Q96F80 G3XAD6 Q499Y4 Q49AU3 Q6UN15 Q7Z608 Q0VGE0 Q9H077 Q8WVN3 B4DIR3
Accessions CAH05656 EAX05445 EAX05446 EAX05447 EAX05448 EAX05449 Q6UN15 AF161429 AAF28989 AK090938 AK123992 AK295737 BAG58575 AK300398 BAG62129 AK308145 AL136910 CAB66844 AM392758 CAL37636 AY366510 AAQ88277 BC011543 AAH11543 BC017724 AAH17724 BC024016 AAH24016 BC026724 BC052959 AAH52959 BC062768 BC110383 AAI10384 DN990103 XM_005265768 XP_005265825 XM_005265769 XP_005265826 XM_005265770 XP_005265827 XM_005265771 XP_005265828 XM_005265772 XP_005265829 XM_005265773 XP_005265830 XM_005265774 XP_005265831 XM_005265775 XP_005265832 XM_005265776 XP_005265833 XM_005265777 XP_005265834 XM_005265778 XP_005265835 XM_005265779 XP_005265836 XM_005265780 XP_005265837 XM_005265781 XP_005265838 XM_005265782 XP_005265839 NM_001134937 NP_001128409 NM_001134938 NP_001128410 NM_030917 NP_112179
Function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex. {ECO:0000269|PubMed:14749727}.
Subcellular Location Nucleus.
Top Pathways mRNA surveillance pathway

FIP1L1 Antibody - 3213 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of total cell lysates from EOL1, A10 and NIH/3T3 cells, using FIP1L1 Antibody.

FIP1L1 (C-10) - sc-398392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FIP1L1 (C-10): sc-398392. Western blot analysis of FIP1L1 expression in Jurkat (A), K-562 (B), HeLa (C) and WiDR (D) whole cell lysates.

FIP1L1 (T-18) - sc-104243 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FIP1L1 (T-18): sc-104243. Western blot analysis of FIP1L1 expression in Hep G2 whole cell lysate.

Anti-FIP1L1 antibody - ab80272 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling FIP1L1 with ab80272 at 1/5000 (0.2µg/ml). Detection: DAB.

Anti-FIP1L1 antibody - ab80271 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pancreatic islet cell tumor tissue labelling FIP1L1 with ab80271 at 1/1000 (1µg/ml). Detection: DAB.

Anti-FIP1L1 antibody - ab84670 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human pancreatic islet cell tumor, using 1/100 ab84670 followed by DAB staining.

Anti-HFip1 / FIP1L1 Antibody - LS-C307550 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HFip1 / FIP1L1 Antibody (aa509-558) - LS-C30444 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-HFip1 / FIP1L1 Antibody (aa544-594) - LS-C288257 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human FIP1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-FIP1 used at a dilution of 1:5000 (0.2 Detection: DAB.

Anti-HFip1 / FIP1L1 Antibody (aa1-50) - LS-C288254 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human FIP1 by Immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit anti-FIP1 used at a dilution of 1:1000 (1 Detection: DAB.

Anti-HFip1 / FIP1L1 Antibody - LS-C333777 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of K562 cell lines, using FIP1L1 antibody. .

Anti-HFip1 / FIP1L1 Antibody - LS-C346244 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of A549 cell using FIP1L1 antibody.

Anti-HFip1 / FIP1L1 Antibody (aa544-594) - LS-C286532 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human FIP1 by Immunohistochemistry. Sample: FFPE section of human skin cancer. Antibody: Affinity purified rabbit anti-FIP1 used at a dilution of 1:100.

FIP1L1 Antibody - NBP1-85064 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FIP1L1 Antibody [NBP1-85064] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

FIP1L1 Antibody - NB100-74589 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Antibody - NB100-74588 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Antibody (2H4) - H00081608-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H4
Sandwich ELISA: FIP1L1 Antibody (2H4) [H00081608-M05] - Detection limit for recombinant GST tagged FIP1L1 is 0.1 ng/ml as a capture antibody.

FIP1L1 Polyclonal Antibody - bs-13173R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13173R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13173R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13173R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Polyclonal Antibody, Cy3 Conjugated - bs-13173R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Polyclonal Antibody, Cy5 Conjugated - bs-13173R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Polyclonal Antibody, Cy5.5 Conjugated - bs-13173R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FIP1L1 Polyclonal Antibody, Cy7 Conjugated - bs-13173R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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