FIP1L1

Gene Symbol FIP1L1
Entrez Gene 81608
Alt Symbol FIP1, Rhe, hFip1
Species Human
Gene Type protein-coding
Description factor interacting with PAPOLA and CPSF1
Other Description FIP1 like 1|FIP1-like 1 protein|FIP1L1 cleavage and polyadenylation specific factor subunit|factor interacting with PAP|pre-mRNA 3'-end-processing factor FIP1|rearranged in hypereosinophilia
Swissprots Q96F80 G3XAD6 Q499Y4 Q49AU3 Q6UN15 Q7Z608 Q0VGE0 Q9H077 Q8WVN3 B4DIR3
Accessions CAH05656 EAX05445 EAX05446 EAX05447 EAX05448 EAX05449 Q6UN15 AF161429 AAF28989 AK090938 AK123992 AK295737 BAG58575 AK300398 BAG62129 AK308145 AL136910 CAB66844 AM392758 CAL37636 AY366510 AAQ88277 BC011543 AAH11543 BC017724 AAH17724 BC024016 AAH24016 BC026724 BC052959 AAH52959 BC062768 BC110383 AAI10384 DN990103 XM_005265768 XP_005265825 XM_005265769 XP_005265826 XM_005265770 XP_005265827 XM_005265771 XP_005265828 XM_005265772 XP_005265829 XM_005265773 XP_005265830 XM_005265774 XP_005265831 XM_005265775 XP_005265832 XM_005265776 XP_005265833 XM_005265777 XP_005265834 XM_005265778 XP_005265835 XM_005265779 XP_005265836 XM_005265780 XP_005265837 XM_005265781 XP_005265838 XM_005265782 XP_005265839 NM_001134937 NP_001128409 NM_001134938 NP_001128410 NM_030917 NP_112179
Function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex. {ECO:0000269|PubMed:14749727}.
Subcellular Location Nucleus.
Top Pathways mRNA surveillance pathway

FIP1L1 CRISPR/Cas9 KO Plasmid (h) - sc-413438 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FIP1L1 HDR Plasmid (h) - sc-413438-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FIP1L1 Double Nickase Plasmid (h) - sc-413438-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FIP1L1 Double Nickase Plasmid (h2) - sc-413438-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FIP1L1 CRISPR Activation Plasmid (h) - sc-413438-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FIP1L1 CRISPR Activation Plasmid (h2) - sc-413438-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FIP1L1 Lentiviral Activation Particles (h) - sc-413438-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FIP1L1 Lentiviral Activation Particles (h2) - sc-413438-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FIP1L1 siRNA (h) - sc-89183 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FIP1L1 shRNA Plasmid (h) - sc-89183-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FIP1L1 shRNA (h) Lentiviral Particles - sc-89183-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU124901 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8700 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8700 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01278 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01278

FIP1L1 siRNA (Human) - CRJ3018 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FIP1L1 - MBS8216043 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FIP1L1 (NM_030917.3) - SHH295081 from Creative biogene

Category siRNA
Species Reactivities Human

Human FIP1L1 siRNA - orb273519 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FIP1L1 shRNA Plasmid (Human) - CHJ3018 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FIP1L1 miRNA 3'UTR clone - MiUTR3H-09384 from Creative biogene

Species Reactivities Human

FIP1L1 miRNA 3'UTR clone - MiUTR3H-09385 from Creative biogene

Species Reactivities Human

FIP1L1 miRNA 3'UTR clone - MiUTR3H-09386 from Creative biogene

Species Reactivities Human
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