Il1b

Gene Symbol Il1b
Entrez Gene 16176
Alt Symbol IL-1beta, Il-1b
Species Mouse
Gene Type protein-coding
Description interleukin 1 beta
Other Description IL-1 beta|interleukin-1 beta
Swissprots P10749 Q2M4J6
Accessions AAX90604 CAA28637 EDL28238 P10749 AK156396 AK157245 AK168047 BAE40029 AK224980 AK225002 AK225003 BC011437 AAH11437 M15131 AAA39276 XM_006498795 XP_006498858 NM_008361 NP_032387
Function Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Subcellular Location Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Top Pathways Cytosolic DNA-sensing pathway, Apoptosis, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Toll-like receptor signaling pathway

IL-1β siRNA (m) - sc-39616 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IL-1β shRNA Plasmid (m) - sc-39616-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IL-1β shRNA (m) Lentiviral Particles - sc-39616-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN33759 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

IL1B siRNA (Mouse) - CRM2050 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

IL1B siRNA (Rat) - CRR0002 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

IL1B - MBS8215211 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse IL1B (NM_008361.3) - SHH318493 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Il1b(NM_008361.3) - SHL172074 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse IL1B siRNA - orb281526 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

IL1B shRNA Plasmid (Mouse) - CHM2050 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

IL1B shRNA Plasmid (Rat) - CHR0002 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Rat

IL1B miRNA 3'UTR clone - MiUTR1M-05989 from Creative biogene

Species Reactivities Mouse
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