PELO
| Gene Symbol | PELO |
|---|---|
| Entrez Gene | 53918 |
| Alt Symbol | CGI-17, PRO1770 |
| Species | Human |
| Gene Type | protein-coding |
| Description | pelota homolog (Drosophila) |
| Other Description | protein pelota homolog |
| Swissprots | Q9Y306 Q9BRX2 Q9GZS6 |
| Accessions | AAG22575 EAW54864 EAW54870 Q9BRX2 AF118075 AAF22019 AF132951 AAD27726 AF139828 AAG22574 AK025729 AK056144 BAG51633 AK312633 AY117399 AAM89414 BC005889 AAH05889 BC007249 AAH07249 BC007650 AAH07650 BC022789 AAH22789 DQ892950 ABM83876 DQ896198 ABM87197 NM_015946 NP_057030 |
| Function | Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). {ECO:0000250, ECO:0000305}. |
| Subcellular Location | Nucleus {ECO:0000305}. Cytoplasm {ECO:0000250}. |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:11060452}. |
| Top Pathways | mRNA surveillance pathway |
PELO-Over-expression-Lysate - LY15341a from Abgent, a WuXi AppTec company
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PELO 293T Cell Transient Overexpression Lysate(Denatured) - H00053918-T01 from Acris Antibodies
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PELO overexpression lysate - LY414299 from Acris Antibodies
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PELO 293 Cell Lysate - 406889 from ABBIOTEC
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PELO Overexpression Lysate (Native) - NBL1-14284 from Novus Biologicals
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PELO (h2): 293T Lysate - sc-170856 from Santa Cruz Biotechnology
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PELO Over-expression Lysate Product - GWB-A7287A from Genway Biotech
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PELO Overexpression Lysate (Denatured) - H00053918-T01 from Novus Biologicals
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PELO Overexpression Lysate (Denatured) - H00053918-T02 from Novus Biologicals
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Panoply™ Human PELO Knockdown Stable Cell Line - CSC-DC011586 from Creative biogene
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