PELO

Gene Symbol PELO
Entrez Gene 53918
Alt Symbol CGI-17, PRO1770
Species Human
Gene Type protein-coding
Description pelota homolog (Drosophila)
Other Description protein pelota homolog
Swissprots Q9Y306 Q9BRX2 Q9GZS6
Accessions AAG22575 EAW54864 EAW54870 Q9BRX2 AF118075 AAF22019 AF132951 AAD27726 AF139828 AAG22574 AK025729 AK056144 BAG51633 AK312633 AY117399 AAM89414 BC005889 AAH05889 BC007249 AAH07249 BC007650 AAH07650 BC022789 AAH22789 DQ892950 ABM83876 DQ896198 ABM87197 NM_015946 NP_057030
Function Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). {ECO:0000250, ECO:0000305}.
Subcellular Location Nucleus {ECO:0000305}. Cytoplasm {ECO:0000250}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:11060452}.
Top Pathways mRNA surveillance pathway

PELO CRISPR/Cas9 KO Plasmid (h) - sc-405192 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PELO HDR Plasmid (h) - sc-405192-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PELO Double Nickase Plasmid (h) - sc-405192-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PELO Double Nickase Plasmid (h2) - sc-405192-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PELO CRISPR Activation Plasmid (h) - sc-405192-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PELO CRISPR Activation Plasmid (h2) - sc-405192-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PELO Lentiviral Activation Particles (h) - sc-405192-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PELO Lentiviral Activation Particles (h2) - sc-405192-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PELO siRNA (h) - sc-91932 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PELO shRNA Plasmid (h) - sc-91932-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PELO shRNA (h) Lentiviral Particles - sc-91932-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU134981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16617 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16617 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06799 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06799

PELO siRNA (Human) - CRH9999 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PELO (NM_015946.4) - SHH373468 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PELO(NM_015946.4) - SHR095328 from Creative biogene

Category siRNA
Species Reactivities Human

Human PELO siRNA - orb270501 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PELO shRNA Plasmid (Human) - CHH9999 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PELO miRNA 3'UTR clone - MiUTR1H-07780 from Creative biogene

Species Reactivities Human
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