NEUROD2

Gene Symbol NEUROD2
Entrez Gene 4761
Alt Symbol NDRF, bHLHa1
Species Human
Gene Type protein-coding
Description neuronal differentiation 2
Other Description class A basic helix-loop-helix protein 1|neuroD-related factor|neurogenic basic-helix-loop-helix protein|neurogenic differentiation 2|neurogenic differentiation factor 2
Swissprots Q15784 Q9UQC6 Q8TBI7
Accessions AAC26058 EAW60579 Q15784 AB021742 BAA77569 AW134767 BC022481 AAH22481 BT019365 AAV38172 XM_005257409 XP_005257466 XM_011524851 XP_011523153 NM_006160 NP_006151
Function Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.

Neuro D2 CRISPR/Cas9 KO Plasmid (h) - sc-405138 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuro D2 HDR Plasmid (h) - sc-405138-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuro D2 Double Nickase Plasmid (h) - sc-405138-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuro D2 Double Nickase Plasmid (h2) - sc-405138-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuro D2 CRISPR Activation Plasmid (h) - sc-405138-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuro D2 CRISPR Activation Plasmid (h2) - sc-405138-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuro D2 Lentiviral Activation Particles (h) - sc-405138-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuro D2 Lentiviral Activation Particles (h2) - sc-405138-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuro D2 siRNA (h) - sc-94081 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neuro D2 shRNA Plasmid (h) - sc-94081-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neuro D2 shRNA (h) Lentiviral Particles - sc-94081-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NeuroD2 RNAi - H00004761-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN15225 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15225 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10302 from Sigma-Aldrich

Category miRNA

NEUROD2 siRNA (Human) - CRH3161 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NEUROD2 (NM_006160.3) - SHH351564 from Creative biogene

Category siRNA
Species Reactivities Human

Human NEUROD2 siRNA - orb263663 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NEUROD2 shRNA Plasmid (Human) - CHH3161 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NEUROD2 miRNA 3'UTR clone - MiUTR3H-04351 from Creative biogene

Species Reactivities Human
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