Gene Symbol | NEUROD2 |
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Entrez Gene | 4761 |
Alt Symbol | NDRF, bHLHa1 |
Species | Human |
Gene Type | protein-coding |
Description | neuronal differentiation 2 |
Other Description | class A basic helix-loop-helix protein 1|neuroD-related factor|neurogenic basic-helix-loop-helix protein|neurogenic differentiation 2|neurogenic differentiation factor 2 |
Swissprots | Q15784 Q9UQC6 Q8TBI7 |
Accessions | AAC26058 EAW60579 Q15784 AB021742 BAA77569 AW134767 BC022481 AAH22481 BT019365 AAV38172 XM_005257409 XP_005257466 XM_011524851 XP_011523153 NM_006160 NP_006151 |
Function | Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. |
Neuro D2 (G-10) - sc-365896 from Santa Cruz Biotechnology
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Neuro D2 (A-13) - sc-107811 from Santa Cruz Biotechnology
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Neuro D2 (H-75) - sc-98674 from Santa Cruz Biotechnology
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Anti-NeuroD2 antibody - ab104430 from Abcam
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Anti-NeuroD2 antibody - ab168932 from Abcam
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Anti-NeuroD2 antibody - ab166926 from Abcam
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Anti-NeuroD2 antibody - ab66607 from Abcam
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Anti-NeuroD2 antibody - ab137179 from Abcam
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Anti-NeuroD2 antibody [EPR5135] - ChIP Grade - ab109406 from Abcam
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Anti-NEUROD2 Antibody - LS-C9246 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (aa362-375) - LS-C55163 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (aa23-37) - LS-C186564 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (aa174-382) - LS-C191471 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (Asp94) - LS-C192017 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (aa71-120) - LS-C30916 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (C-Terminus) - LS-C30204 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (aa61-110) - LS-C119075 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (aa45-94) - LS-C200257 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (clone 3E7) - LS-C197769 from LifeSpan Bioscience
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Anti-NEUROD2 Antibody (Internal, clone EPR5135) - LS-C138361 from LifeSpan Bioscience
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NeuroD2 Antibody - AF2775 from Novus Biologicals
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NeuroD2 Antibody - NBP2-32545 from Novus Biologicals
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NeuroD2 Antibody - NBP2-26068 from Novus Biologicals
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NeuroD2 Antibody - H00004761-D01P from Novus Biologicals
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NeuroD2 Antibody - NBP1-31270 from Novus Biologicals
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