ENOX2

Gene Symbol ENOX2
Entrez Gene 10495
Alt Symbol APK1, COVA1, tNOX
Species Human
Gene Type protein-coding
Description ecto-NOX disulfide-thiol exchanger 2
Other Description APK1 antigen|cytosolic ovarian carcinoma antigen 1|tumor-associated hydroquinone oxidase
Swissprots A8K1C2 Q5VTJ2 Q16206 Q5VTJ1 Q9UH82 A8K197 Q8WUX0 Q9NTP6
Accessions CAM12255 EAX11796 EAX11797 Q16206 AF207881 AAF20934 AI540639 AK000353 AK289812 BAF82501 AK289837 BAF82526 AL133207 CAB61581 BC019254 AAH19254 BC108713 AAI08714 BC139781 AAI39782 BC140874 AAI40875 BU160341 DB128861 S72904 AAB30428 XM_005262354 XP_005262411 XM_011531244 XP_011529546 XM_011531245 XP_011529547 XM_011531246 XP_011529548 XM_011531247 XP_011529549 XM_011531248 XP_011529550 XM_011531249 XP_011529551 XM_011531250 XP_011529552 XM_011531251 XP_011529553 XM_011531252 XP_011529554 NM_001281736 NP_001268665 NM_006375 NP_006366 NM_182314 NP_872114
Function May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide- thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock. {ECO:0000269|PubMed:12356293, ECO:0000269|PubMed:9932650}.
Subcellular Location Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
Tissue Specificity Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Not found in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells. Found on the cell borders of renal, kidney and ovarian carcinomas but not on the borders of surrounding non-cancerous stromal cells.

Anti-ENOX1 antibody - ab169668 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ENOX1 antibody (ab169668) at 1 µg/mlLane 1 : ENOX1-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-ENOX1 antibody - ab83540 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ENOX1 antibody (ab83540) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-ENOX1 antibody - C-terminal - ab187120 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ENOX1 antibody - C-terminal (ab187120) at 1/1000 dilutionLane 1 : HeLa total cell extractLane 2 : Jurkat total cell extract

Anti-ENOX2 antibody - N-terminal - ab171420 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ENOX2 antibody - N-terminal (ab171420) at 1/100 dilution + Jurkat cell line lysate at 35 µg

Anti-ENOX2 Antibody (aa1-30, AP) - LS-C256697 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENOX2 Antibody (aa454-465) - LS-C61732 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ENOX2 Antibody (aa1-30, APC) - LS-C256699 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENOX2 Antibody (aa1-30, Biotin) - LS-C259263 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENOX2 Antibody (aa1-30, Azide-free, HRP) - LS-C259265 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENOX2 Antibody (aa1-30, FITC) - LS-C259264 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENOX2 Antibody (aa1-30, PE) - LS-C259266 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENOX2 Antibody (aa1-30) - LS-C321113 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ENOX2 Antibody (aa155-204) - LS-C135645 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ENOX2 antibody LS-C135645 Western blot of U937 cell lysate.

Anti-ENOX2 Antibody - LS-C346209 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of U20S cell using ENOX2 antibody. Blue: DAPI for nuclear staining.

Anti-ENOX2 Antibody (aa1-30) - LS-C167764 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ENOX2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

ENOX2 Antibody - NBP1-79778 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ENOX2 Antibody [NBP1-79778] - U937 cell lysate, concentration 0.2-1 ug/ml.

ENOX2 Antibody - NBP1-89038 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: ENOX2 Antibody [NBP1-89038] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells.

ENOX2 Antibody - H00010495-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-ENOX2 antibody produced in rabbit - SAB2107470 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ENOX2: <B>Cat. No. SAB2107470</B>: Western blot analysis of ENOX2 with ENOX2 (ecto-NOX disulfide-thiol exchanger 2) antibody against the N terminal of ENOX2 (50 μg) antibody at 1.0 μg/mL.

ANTI-ENOX2 (N-TERM) antibody produced in rabbit - SAB1303576 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>ENOX2 (N-term): <B>Cat. No. SAB1303576</B>: ENOX2 in Human stomach tissue with ENOX2 antibody (N-term) at 12.5 μg/mL.

Anti-ENOX2 antibody produced in rabbit - HPA000514 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ENOX2: <B>Cat. No. HPA000514</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human smooth muscle tissue showing cytoplasmic and/or membranous staining.

ENOX2 Antibody - middle region (ARP59870_P050) - ARP59870_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ENOX2 antibody - N-terminal region (ARP59871_P050) - ARP59871_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ENOX2-Antibody-N-term - AP12957a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ENOX2 Antibody (N-term) (Cat. #AP12957a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ENOX2 antibody detected the ENOX2 protein (arrow).

ENOX2--APK1-Antibody-internal-region - AF2617a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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