| Gene Symbol |
AOC2
|
| Entrez Gene |
314
|
| Alt Symbol |
DAO2, RAO
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
amine oxidase, copper containing 2 (retina-specific)
|
| Other Description |
SSAO|retina-specific copper amine oxidase|semicarbazide-sensitive amine oxidase
|
| Swissprots |
O75105 O75106 Q9UNY0 Q4TTW5 O00120 A5PKW2
|
| Accessions |
AAY43129 BAA32589 BAA32590 EAW60895 EAW60896 O75106 AF081363 AAD39345 BC142641 AAI42642 CA425343 CN355968 D88213 BAA19001 DQ426861 ABD90530 NM_001158 NP_001149 NM_009590 NP_033720
|
| Function |
Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina. {ECO:0000269|PubMed:17400359, ECO:0000269|PubMed:19588076}.
|
| Subcellular Location |
Isoform 1: Cell membrane; Peripheral membrane protein. Note=Present on the surface of the cells.
|
| Tissue Specificity |
Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis. {ECO:0000269|PubMed:12755418, ECO:0000269|PubMed:17400359, ECO:0000269|PubMed:19588076}.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism
|